Results 91 to 100 of about 834,074 (296)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Sustainable EnvironmentObjective: This paper serves a triadic purpose: To investigate manufacturers’ adoption of circularity science in supply chains and its perceived viability to promote sustainable performance through assessing supply chain anthropogenic practices ...
Mary Aming’a +2 more
doaj +1 more source
Study of a circular Gaussian transition in an optical speckle field [PDF]
Journal of the European Optical Society-Rapid Publications, 2008 We propose a numerical approach to study optical speckle fields generated by various conditions of surface roughness and illumination, without any a priori assumption concerning the properties of the scattered field. By overcoming the limitations imposed
Bergoënd Isabelle +2 more
doaj +1 more source
, 2021 Although a circular economy promotes economic and environmental benefits, knowledge gaps remain surrounding the application of these concepts to food systems.
K. Koppelmäki, J. Helenius, R. Schulte
semanticscholar +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Practical considerations for assessing product-related circularity and product social considerations within LCSA: insights from industry [PDF]
The report provides the findings of 21 in-depth industry interviews with the aim to gain insight into if and how product circularity is understood, implemented, and measured by industry.
Charter, Martin, Sanchez Moreno, Lilian
core +5 more sources
Urban ScienceThis article explores how the principles of circularity, applied to urban food systems, could contribute to catalysing a transition towards more sustainable cities, working on the premise that food security is a key pillar of urban resilience.
Sandrine Simon
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Frontiers in SustainabilityIntroductionThe transition toward a circular economy (CE) is a key strategy for sustainable production and consumption, yet its contribution to sustainability depends on how it is assessed.
Dieuwertje Schrijvers +10 more
doaj +1 more source