Results 71 to 80 of about 30,857 (268)

Circular Aggregates – Crushed Concrete Aggregates for Concrete Applications

open access: yesNordic Concrete Research
Concrete waste is utilized in Sweden mostly for backfilling in road applications and building landfills. The techniques for recycling concrete to replace natural aggregates are in place and makes it possible to produce circular and climate reduced ...
Loubani Habib   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Influence of Machine Tool Operating Conditions on the Resulting Circularity and Positioning Accuracy

open access: yesMachines
The operating conditions of the production process significantly influence the resulting dimensional and form accuracy of the workpiece. The operating conditions include the position of the workpiece location, with internal and external heat sources ...
Matej Sarvas   +5 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

CIRCULAR LAW

open access: yesAdvances in Statistics, 1997
This paper studies the conjecture that the empirical spectral distribution of an \(n\times n\) matrix of i.i.d. entries \(\xi_{kj} =(1/ \sqrt n) x_{kj}\) and \(\{x_{kj},\;k,j=1,2, \dots\}\) forming an infinite double array of i.i.d. complex random variables converges to the uniform distribution over the unit disc on the complex plane, which is called ...
openaire   +2 more sources

Fostering Directions for Digital Technology Adoption in Sustainable and Circular Fashion: Toward the Circular Fashion-Tech Lab

open access: yesSystems
The fashion sector, recognized for its resource-intensive methods, is currently encountering pressing sustainability issues due to its substantial dependence on natural resources, extensive utilization of chemicals, and exploitation of labor within its ...
Daria Casciani, Erminia D’Itria
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

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