Results 61 to 70 of about 30,857 (268)

Circular Insanity [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1885
n ...
openaire   +1 more source

Us and Them: A Vision of Heroes on the Move in John McGahern’s Fiction

open access: yesAmerican, British and Canadian Studies Journal, 2016
Current explorations of migration in fiction focus on innovative perspectives, linking memory and trauma with the concepts of exile and conflict.
Radler Dana
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Responsibility-Internalism Collapses: Conceptual, Normative, and Relational Challenges [PDF]

open access: yesJournal of Philosophical Investigations
Moral responsibility is a fundamental component of ethics, shaping our understanding of accountability, blame, and praise. Responsibility-internalism, which holds that moral responsibility is grounded in some internal mental states, such as beliefs ...
Elahe Sadeqian, Ahmad Fazeli
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Heritage for a sustainable future – The theoretical principle of reversibility and its reflections on architecture

open access: yesAgathón
The theme of reversibility in architecture focuses on the addition of the new to the existing and how this ‘input’ can be made reversible to preserve the pre-existing ideas budding in the Italian culture of Restoration and promoting new ideas in ...
Roberta Fonti
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

From Digital Transformation to Circular Growth: The Role of Economic Complexity and Eco-Innovation in Africa’s Sustainable Future

open access: yesEconomies
This study investigates how eco-innovation, digitalization, and economic complexity drive the circular economy in African economies between 2000 and 2024.
Hela Mili
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Annual Circular [PDF]

open access: yesThe American Journal of the Medical Sciences
n ...
openaire   +1 more source

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