Results 51 to 60 of about 30,857 (268)
Frontiers in SustainabilityIntroductionThe transition toward a circular economy (CE) is a key strategy for sustainable production and consumption, yet its contribution to sustainability depends on how it is assessed.
Dieuwertje Schrijvers +10 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Urban ScienceThis article explores how the principles of circularity, applied to urban food systems, could contribute to catalysing a transition towards more sustainable cities, working on the premise that food security is a key pillar of urban resilience.
Sandrine Simon
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Contextual Theory, or Theorizing between the Discursive and the Material [PDF]
Analytical Approaches to World Music, 2020 How can ethnography and music theory and analysis richly inform one another? One way is to incorporate the words and concepts used by high-level practitioners to build a theoretical scaffolding—to build an analytic framework that stems directly from ...
Stover, Chris
doaj
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Non-parametric methods for circular-circular and circular-linear [PDF]
, 2011 We present a non-parametric approach for the estimation of the bivariate distribution of two circular variables and the modelling of the joint distribution of a circular and a linear variable. We combine nonparametric estimates of the marginal densities of the circular and linear components with the use of class of nonparametric copulas, known as ...
Ausín Olivera, María Concepción +2 more
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Cognitive Science, 2002 AbstractGood informal arguments offer justification for their conclusions. They go wrong if the justifications double back, rendering the arguments circular. Circularity, however, is not necessarily a single property of an argument, but may depend on (a) whether the argument repeats an earlier claim, (b) whether the repetition occurs within the same ...
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FoodsThe European Union aims for climate neutrality by 2050 and has proposed the Packaging and Packing Waste Regulation (PPWR) to promote a circular economy, focusing on reducing packaging waste.
Michelle Klein +4 more
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source