Results 61 to 70 of about 28,809 (247)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Heritage for a sustainable future – The theoretical principle of reversibility and its reflections on architecture

open access: yesAgathón
The theme of reversibility in architecture focuses on the addition of the new to the existing and how this ‘input’ can be made reversible to preserve the pre-existing ideas budding in the Italian culture of Restoration and promoting new ideas in ...
Roberta Fonti
doaj   +1 more source

Fundamental Cell Morphologies Examined With Cryo-TEM of the Species in the Novel Five Genera Robustly Correlate With New Classification in Family Mycobacteriaceae

open access: yesFrontiers in Microbiology, 2020
A recent study proposed the novel classification of the family Mycobacteriaceae based on the genome analysis of core proteins in 150 Mycobacterium species.
Hiroyuki Yamada   +11 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

From Digital Transformation to Circular Growth: The Role of Economic Complexity and Eco-Innovation in Africa’s Sustainable Future

open access: yesEconomies
This study investigates how eco-innovation, digitalization, and economic complexity drive the circular economy in African economies between 2000 and 2024.
Hela Mili
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Circular Aggregates – Crushed Concrete Aggregates for Concrete Applications

open access: yesNordic Concrete Research
Concrete waste is utilized in Sweden mostly for backfilling in road applications and building landfills. The techniques for recycling concrete to replace natural aggregates are in place and makes it possible to produce circular and climate reduced ...
Loubani Habib   +2 more
doaj   +1 more source

Circular cities

open access: yesUrban Studies, 2019
A circular approach to the way in which we manage the resources consumed and produced in cities – materials, energy, water and land – will significantly reduce the consumption of finite resources globally. It will also help to address urban problems including resource security, waste disposal, greenhouse gas emissions, pollution, heating, drought and ...
openaire   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Influence of Machine Tool Operating Conditions on the Resulting Circularity and Positioning Accuracy

open access: yesMachines
The operating conditions of the production process significantly influence the resulting dimensional and form accuracy of the workpiece. The operating conditions include the position of the workpiece location, with internal and external heat sources ...
Matej Sarvas   +5 more
doaj   +1 more source

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