This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
Effect and mechanism of Tetramethylpyrazine in repair of sciatic nerve injury in rats
Objective Observing the effects of Tetramethylpyrazine (TMP) on the expression of Collagen IV and Laminin in neurovascular basement membrane and the apoptosis of vascular endothelial cells, and to study the mechanism of TMP in the treatment of sciatic ...
Yang Li+4 more
doaj +1 more source
Comparative Mutational Profiling of Hematopoietic Progenitor Cells and Circulating Endothelial Cells (CECs) in Patients with Primary Myelofibrosis. [PDF]
Farina M+10 more
europepmc +1 more source
Endothelial Replacement and Angiogenesis in Arteriosclerotic Lesions of Allografts Are Contributed by Circulating Progenitor Cells [PDF]
Yanhua Hu+3 more
openalex +1 more source
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan+4 more
wiley +1 more source
Number and Adhesive Properties of Circulating Endothelial Progenitor Cells in Patients With In-Stent Restenosis [PDF]
Jacob George+8 more
openalex +1 more source
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana+2 more
wiley +1 more source
Relationship of Circulating Endothelial Cells With Obesity and Cardiometabolic Risk Factors in Children and Adolescents. [PDF]
Soltero EG+11 more
europepmc +1 more source
Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy
Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi+6 more
wiley +1 more source
Role of circulating endothelial cells in assessing the severity of systemic sclerosis and predicting its clinical worsening. [PDF]
Di Martino ML+7 more
europepmc +1 more source