Results 121 to 130 of about 367,441 (304)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Research Progress on Circulating Inflammatory Proteins and Osteonecrosis of the Femoral Head

Journal of Contemporary Medical Practice
Osteonecrosis of the femoral head (ONFH) is a common orthopedic condition with a complex pathogenesis involving multiple factors. Recent studies have highlighted the significant role of inflammation in its development. Circulating inflammatory proteins, such as cytokines, chemokines, and acute phase response proteins, contribute to the onset and ...
Huaao Wang, Jian Zhang
openaire   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Physical activity in older men: longitudinal associations with inflammatory and hemostatic biomarkers, N-terminal pro-brain natriuretic peptide, and onset of coronary heart disease and mortality [PDF]

, 2014
Objectives: To examine associations between habitual physical activity (PA) and changes in PA and onset of coronary heart disease (CHD) and the pathways linking PA to CHD.
Jefferis, BJ, Peter H. Whincup, Olia Papacosta, Whincup, PH, Lucy T. Lennon, S. Goya Wannamethee, Papacosta, O, Barbara J. Jefferis, Lennon, LT, Goya Wannamethee, S   +9 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Causal Association Between Circulating Inflammatory Proteins and Autoimmune Liver Disease: a Bidirectional Two-Sample Mendelian Randomization Study

ImmunoTargets and Therapy
Lina Leng,1,* Ying Li,2,* Tao Xu,3 Jingfang Shen,1 Lianju Li,1 Xiaoli Li1 1Department of Rheumatology, Xingtai People’s Hospital, Xingtai, 054001, Hebei Province, People’s Republic of China; 2Department of Oncology, 82 Group Hospital of Chinese ...
Leng L, Li Y, Xu T, Shen J, Li L, Li X
doaj  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

The mediation of circulating inflammatory proteins in the causal pathway from immune cells to osteoarthritis

Journal of Orthopaedic Surgery and Research
Observational studies have found that immune cells and circulating inflammatory proteins play a dual role in the progression of osteoarthritis, but the exact mechanism remains unclear. Therefore, this study aimed to investigate whether the causal relationship between immune cells and Knee OA is mediated by circulating inflammatory proteins.A two-sample
Yuan, Ye, Liang, Xingyu, Kang, Sining, Liu, Yanrong   +3 more
openaire   +3 more sources

The translational relevance of the Annexin A1 pathway in inflammatory pathologies: opportunities for novel therapeutic development [PDF]

, 2009
PhDEndogenous anti-inflammatory mediators form a complex network triggered in the host to dampen cell activation and promote resolution of inflammation.
Dalli, Jesmond
core  

Montmorency cherries reduce the oxidative stress and inflammatory responses to repeated days high-intensity stochastic cycling [PDF]

, 2014
This investigation examined the impact of Montmorency tart cherry concentrate (MC) on physiological indices of oxidative stress, inflammation and muscle damage across 3 days simulated road cycle racing.
Stevenson, Emma, Phillip Bell, Bell, Phillip, Gareth Davison, Emma Stevenson, Howatson, Glyn, Glyn Howatson, Davison, Gareth, Walshe, Ian, Ian Walshe   +9 more
core   +1 more source