Results 111 to 120 of about 367,441 (304)

Human epicardial adipose tissue expresses a pathogenic profile of adipocytokines in patients with cardiovascular disease [PDF]

, 2006
Introduction: Inflammation contributes to cardiovascular disease and is exacerbated with increased adiposity, particularly omental adiposity; however, the role of epicardial fat is poorly understood.
Domenico Pagano, Bonser, Robert S., Baker Adam R, AdamR Baker, Pagano, Domenico, PhilipG McTernan, NancyF da Silva, AlisonL Harte, RobertS Bonser, Kumar Sudhesh, Baker, Adam R., Pagano Domenico, Kumar, Sudhesh, Quinn, David W., Bonser Robert S, McTernan Philip G, Sudhesh Kumar, da Silva Nancy F, DavidW Quinn, Harte, A. L. (Alison L.), Harte Alison L, Quinn David W, Fernandez da Silva, Nancy, McTernan, P. G. (Philip G.)   +23 more
core   +1 more source

The Causal Relationship Between Circulating Inflammatory Proteins and Tinnitus: A Mendelian Randomization Study Mediated by Blood Metabolites

Brain and Behavior
Purpose Tinnitus is a complex disease whose pathophysiological mechanisms are still not fully elucidated. Dysregulation of circulating inflammatory proteins and metabolites is thought to play a crucial role in tinnitus pathophysiology, but the causal ...
Keyu Chen, Yuankun Cai
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The Associations of Circulating Inflammatory-Related Proteins with Asthma: A Mendelian Randomization Study

Abstract Background Epidemiological evidence links inflammation to the etiology and pathophysiology of asthma. To assess the causal relationship between circulating inflammation-related proteins and asthma, we performed a two-sample Mendelian randomization (MR) analysis.
Yajun Xiong, Yanbing Sheng, Long Zhang, Yuntao Wei, Yuying Feng, Xiaonan Zhang, Xiang Ma, Tianyi Guo, Shuang Wang, Xiaoya Niu, Mengting Cai, Yu Chen, Jie Zhang, Aiguo Xu   +13 more
openaire   +1 more source

Effects of fatty acids on inflammatory markers studied in vivo and in vitro [PDF]

, 2008
Inflammation involves interactions amongst many different cell types as a defense mechanism of the body. Inflammation is also involved in cardiovascular disease (CVD).
Mohd Yusof, Hayati
core  

Associations of proinflammatory cytokines with the risk of recurrent stroke [PDF]

, 2008
<p><b>Background and Purpose:</b> There are few reports on proinflammatory cytokines and risk of primary or recurrent stroke. We studied the association of interleukin (IL)-6, IL-18, and tumor necrosis factor-α (TNF-α) with recurrent ...
Welsh, P., Chalmers, J., Lowe, G.D., Welsh, P, Woodward, M, Lowe, GD, MacMahon, SW, Neal, B.C., Campbell, DJ, Neal, BC, MacMahon, S.W., Rumley, A., Campbell, D., Chalmers, J, MacMahon, Stephen, Rumley, A, Woodward, M.   +16 more
core   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

The Mediation of Circulating Inflammatory Proteins in the Causal Pathway from Immune Cells to COPD

International Journal of Chronic Obstructive Pulmonary Disease
Observational studies have indicated that immune cells and circulating inflammatory proteins may play a dual role in the progression of COPD; however, the precise mechanisms remain uncertain. The objective of this study was to ascertain the causal relationship between immune cells and COPD and to quantify the potential role of circulating inflammatory ...
Kunrong Yan, Yingjian Wang, Peng Xin
openaire   +4 more sources

Effects of fatty acids on inflammatory markers studies in vitro and in vivo [PDF]

, 2008
Inflammation involves interactions amongst many different cell types as a defense mechanism of the body. Inflammation is also involved in cardiovascular disease (CVD).
Mohd Yusof, Hayati
core  

The relationship between the insulin-like growth factor-1 axis, weight loss, an inflammation-based score and survival in patients with inoperable non-small cell lung cancer [PDF]

, 2010
<b>Background & aims:</b> The involvement of a systemic inflammatory response, as evidenced by the Glasgow Prognostic Score (GPS), is associated with weight loss and poor outcome in patients with non-small cell lung cancer.
Meek, C.L., Wallace, A.M., McMillan, D.C., Forrest, L.M.   +3 more
core   +1 more source