Results 141 to 150 of about 5,745,790 (267)

Mesenchymal phenotype of circulating tumor cells is associated with distant metastasis in breast cancer patients

, 2017
Shirong Zhang,1,* Tiecheng Wu,2,* Xinguo Peng,3 Jian Liu,4 Fang Liu,5 Shiyang Wu,5 Suyan Liu,5 Yan Dong,5 Shujun Xie,1 Shenglin Ma6 1Translational Medicine Research Center, Hangzhou First People’s Hospital, Nanjing Medical University, Hangzhou ...
Liu J, Liu SY, Xie SJ, Dong Y, Zhang SR, Wu SY, Peng XG, Ma SL, Wu TC, Liu F   +9 more
core  

Harnessing the Horse for Human Osteoarthritis: microRNA‐181a‐5p Antisense Oligonucleotides in Clinically Normal Equine Fetlock Joints Are Safe and Well Tolerated

Journal of Orthopaedic Research, Volume 44, Issue 11, November 2026.
ABSTRACT Horses serve as a translational model for human osteoarthritis (OA) due to their comparable joint size, cartilage thickness, and incidence of naturally occurring disease. Overexpression of microRNA‐181a‐5p has been implicated in cartilage degradation in OA, and its inhibition using locked nucleic acid antisense oligonucleotides (LNA‐miR‐181a ...
T. Connor McCorkell, Narman Mortagy, Rodrigo Munevar Luque, Thomas G. Koch, Janet Beeler‐Marfisi, Y. Raja Rampersaud, Jonathan Lamarre, Mohit Kapoor, Judith B. Koenig   +8 more
wiley   +1 more source

CIRCULATING TUMOR CELLS: CLINICAL SIGNIFICANCE IN BREAST CANCER (REVIEW)

, 2017
Circulating tumor cells (CTCs) constitute a heterogeneous population. Some tumor cells are cancer stem cells (CSCs), while others are in the process of the epithelial-mesenchymal transition (EMT); however, most CTCs are neither stem cells nor ...
E. V. Kaigorodova
core   +1 more source

Exosomes in Cancer: The Biology, Function, Diagnosis, and Therapy

MedComm, Volume 7, Issue 11, November 2026.
Tumor‐derived exosomes and nonmembranous extracellular nanoparticles (exomeres/supermeres) constitute a heterogeneous communication network that drives cancer progression. By shuttling functional biomolecules across tissue‐specific barriers, these nanoparticles orchestrate local microenvironmental remodeling, immune suppression, premetastatic niche ...
Jun Wu, Lei Wu, Kang Yang, Kang Xie, Tao Lu, Tiangxiang Huang, Dengfeng Wan, Tao Song, Longbo Zhang   +8 more
wiley   +1 more source

Biosensors for the Isolation and Detection of Circulating Tumor Cells (CTCs) in Point-of-Care Settings. [PDF]

Micromachines (Basel), 2023
Goldstein I, Alyas S, Asghar W, Ilyas A.
europepmc   +1 more source

Liquid Biopsy: Past, Present, and Future

MedComm, Volume 7, Issue 11, November 2026.
Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu, Dianjie Zeng, Keran Zhao, Yuxi Wang, Huijie Hu, Fei Deng, Yinhuai Wang, Liya Sun, Liangmin Fu   +8 more
wiley   +1 more source

Modeling critical interaction for metastasis between circulating tumor cells (CTCs) and platelets adhered to the capillary wall. [PDF]

Comput Methods Programs Biomed, 2023
Milosevic M, Simic V, Nikolic A, Shao N, Kawamura Hashimoto C, Godin B, Leonard F, Liu X, Kojic M.   +8 more
europepmc   +1 more source

Circulating tumor cells and emerging blood biomarkers in breast cancer.

, 2010
To critically review the latest findings concerning the role of circulating tumor cells (CTCs) and other blood biomarkers in breast cancer.Journal ArticleResearch Support, Non-U.S.
Ignatiadis, Michail, Carmen Criscitiello, Sotiriou, Christos, Christos Sotiriou, Michail Ignatiadis, Criscitiello, Carmen   +5 more
core   +1 more source

Primary BPH Stromal Cell Cultures Exhibit Heightened Androgen‐Responsiveness

The Prostate, Volume 86, Issue 15, Page 1508-1517, November 2026.
ABSTRACT Background Benign prostatic hyperplasia (BPH) is the most common disease in aging males. BPH growth is androgen‐dependent, and it appears that androgens preferentially stimulate the growth of BPH as compared to normal prostate. The mechanism of preferential androgen stimulation of BPH growth is not clear.
Wei Chen, Fulu Dong, Mohammad Reza Askarpour, Laura E. Pascal, Rajiv Dhir, Uma Chandran, Bruce L. Jacobs, Donald B. DeFranco, Naoki Yoshimura, Zhou Wang   +9 more
wiley   +1 more source

Design, Synthesis and Biophysical Characterisation of CPP‐PNA Conjugates for Targeting Oncogenic microRNA‐221

Journal of Peptide Science, Volume 32, Issue 11, November 2026.
Cell‐penetrating peptide‐peptide nucleic acid (CPP‐PNA) conjugates that target the oncogenic microRNA‐221‐5p were synthesised using Cu(I)‐catalysed azide‐alkyne cycloaddition (CuAAC) and disulfide‐mediated conjugation strategies. These constructs form highly stable, sequence‐selective PNA/RNA heteroduplexes and demonstrate preliminary antiproliferative
Martina Rotondo, Françoise Illien, Fabienne Burlina, Barbara Biondi   +3 more
wiley   +1 more source