Results 281 to 290 of about 313,286 (312)

From Early Detection To Advanced Therapies: How Circulating Tumor DNA Is Transforming the Care of Colorectal Cancer. [PDF]

Curr Oncol Rep
Yee EJ, McCarter MD, Vogel JD, Schulick RD, Lieu C, Lentz RW.   +5 more
europepmc   +1 more source

Lactylated SPTAN1 Accelerates Hepatocellular Carcinoma Progression by Promoting NOTCH1/HES1 Activation and Immunosuppression

Advanced Science, EarlyView.
This study identifies SPTAN1‐kla as a novel oncogenic driver in HBV‐driven HCC, linking metabolic, epigenetic, and immune mechanisms. SPTAN1‐kla promotes HCC progression via NOTCH1/HES1 activation and immunosuppression. Findings highlight that targeting SPTAN1‐kla provides a framework for HCC treatment to improve clinical outcomes in HBV infected ...
Zengbin Wang, Dongjie Ye, Linqing Wu, Jiayu Liu, Banglun Pan, Zhu Zhang, Xiaoxia Zhang, Yuxin Yao, Nanhong Tang   +8 more
wiley   +1 more source

Comprehensive Analysis of the Value of Dynamic Changes in Circulating Tumor DNA in Small Cell Lung Cancer. [PDF]

JCO Precis Oncol
Ajay A, Ferdousi R, Joseph PL, Durer S, Rezvani A, Chen Z, Wildey GM, Lam M, Fu P, Dowlati A.   +9 more
europepmc   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Circulating Tumor DNA detection in cancer: a comprehensive overview of current detection methods and prospects. [PDF]

Oncologist
de Abreu AR, Wyninckx A, Vandamme T, Op de Beeck K, Van Camp G, Peeters M, Laurent-Puig P, Taieb J, Taly V, Benhaim L.   +9 more
europepmc   +1 more source

METTL1‐Mediated M7G tRNA Modification Promotes Residual Liver Regeneration After Hepatectomy via Translational Control

Advanced Science, EarlyView.
METTL1 and its mediated m7G tRNA modification are significantly up‐regulated after partial hepatectomy (PHx). Overexpression of METTL1 improves the efficiency of liver regeneration after PHx, increases the proliferation of hepatocytes, and accelerates the recovery of liver function.
Manling Huang, Shuirong Lin, Yutong Zhao, Jiale Chen, Linyuan Huang, Yuyao Liu, Zixin Huang, Dongxin An, Yifan Zhang, Zimin Song, Xi Yu, Yunpeng Hua, Jing Wang, Weiwei Wang, Yu Guo, Ming Kuang, Fang Wang, Shuibin Lin, Shunli Shen   +18 more
wiley   +1 more source

Read-level DNA methylation deconvolution enhances circulating tumor DNA detection. [PDF]

Brief Bioinform
Qi T, Lakshmanan LN, Yang Y, Zhou Y, Pan M, Skanderup AJ, Ge Q.   +6 more
europepmc   +1 more source

Real-World Utilization and Performance of Circulating Tumor DNA Monitoring to Predict Recurrence in Solid Tumors

Van‐Anh Nguyen Hoang, Ngoc Lan Nguyen, Duc Nhan Le, Van Son Nguyen, Huong Nguyen Thi, Hien Thi Thu Vu, Heinemann Ho, Hong Minh Le, Tiến Dũng Nguyễn, Huu-Canh Vo, Thanh‐Thuy Thi, Van Tuan Ha, Hoang Duong Nguyen, Marisa Thi, Kim Thi, T. Doanh, Minh Tu Hoang, Hoang‐Giang Vu, Tu Nguyen, Van Thi Phan, Nguyen Huu Tam Phuc, Duy Sinh Nguyen, Hoai‐Nghia Nguyen, Lan N. Tu   +23 more
openalex   +1 more source

Role of Circulating Tumor DNA in Adapting Immunotherapy Approaches in Breast Cancer. [PDF]

Curr Oncol
Kumar S, Pezo RC.
europepmc   +1 more source

Circulating tumor DNA refines consolidation immunotherapy for limited-stage small cell lung cancer patients. [PDF]

Signal Transduct Target Ther
Yang Y, Wu Y, Zhao J, Zhang T, Fei K, Zhao X, Deng L, Zhang Z, Jiang Y, Wang J, Liu W, Wang X, Wang S, Bao H, Wu X, Zhu M, Ou Q, Tang W, Wang L, Wang Z, Bi N.   +20 more
europepmc   +1 more source