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Circulating Tumor DNA in Lymphoma
Current Hematologic Malignancy Reports, 2022Recent advances have been made in circulating tumor DNA (ctDNA), the method to minimally invasive detect lymphoma sensitively with tumor-derived DNA in the blood of patients with lymphomas. This article discusses these various methods of ctDNA detection and the clinical context in which they have been applied to for a variety of lymphoma subtypes.ctDNA
Swetha Kambhampati, Thiruvengadam +1 more
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Circulating tumor DNA analysis for tumor diagnosis
Talanta, 2021Tumor is a kind of abnormal organism generated by the proliferation and differentiation of cells in the body under the action of various initiating and promoting factors, which seriously threatens human life and health. Tumorigenesis is a gradual process that involves multistage reactions and the accumulation of mutations.
Yi-Hui, Wang +3 more
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Circulating Tumor Cells and Circulating Tumor DNA in Urologic Cancers
Urologic Clinics of North America, 2023Liquid biopsies such as circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) have great potential to serve as prognostic and predictive biomarkers in urologic cancers. The possibility of using liquid biopsies for real-time noninvasive and dynamic monitoring of response to therapy has been an active area of investigation.
Ikenna, Madueke +2 more
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Circulating tumor DNA in neuroblastoma
Pediatric Blood & Cancer, 2020AbstractAs a sympathetic nervous system–derived tumor, aggressive neuroblastoma (NB) is currently attracting interest from researchers seeking diagnostic and prognostic markers via less invasive procedures. The analysis of circulating tumor DNA (ctDNA) in peripheral blood can provide genetic information from multiple tumor lesions and is not dependent ...
Meng Wei +3 more
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Circulating Tumor Cells and Circulating Tumor DNA
Annual Review of Medicine, 2012Solid tumors derived from epithelial tissues (carcinomas) are responsible for 90% of all new cancers in Europe, and the main four tumor entities are breast, prostate, lung, and colon cancer. Present tumor staging is mainly based on local tumor extension, metastatic lymph node involvement, and evidence of overt distant metastasis obtained by imaging ...
Catherine, Alix-Panabières +2 more
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2016
Circulating cell-free DNA (ccfDNA)--first identified in 1947--is "naked" DNA that is free-floating in the blood, and derived from both normal and diseased cells. In the 1970s, scientists observed that patients with cancer had elevated levels of ccfDNA as compared to their healthy, cancer-free counterparts.
Heather A, Parsons +2 more
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Circulating cell-free DNA (ccfDNA)--first identified in 1947--is "naked" DNA that is free-floating in the blood, and derived from both normal and diseased cells. In the 1970s, scientists observed that patients with cancer had elevated levels of ccfDNA as compared to their healthy, cancer-free counterparts.
Heather A, Parsons +2 more
openaire +2 more sources
Circulating Tumor DNA and Hepatocellular Carcinoma
Seminars in Liver Disease, 2019AbstractThere is a clear and unmet need for biomarkers in hepatocellular carcinoma (HCC). Circulating cell free deoxyribonucleic acid (cfDNA) is a fragmented DNA subtype, found in the blood circulation. Circulating tumor DNA (ctDNA) is the fraction of total cfDNA, which originates from the primary tumor or metastases in patients with cancer.
Ju Dong, Yang +2 more
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Analysis of Circulating Tumor DNA
2018Circulating tumor DNA (ctDNA) analysis is currently gaining momentum as an innovative methodology for characterizing the tumor genome and monitoring therapeutic efficacy in the multifocal, genetically and spatially heterogeneous plasma cell malignancy, multiple myeloma (MM).
Sridurga, Mithraprabhu, Andrew, Spencer
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