Results 111 to 120 of about 2,903,919 (287)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An objective method to associate local weather extremes with characteristic circulation structures [PDF]

, 2009
In this paper we give methods to find characteristic circulation patterns which are connected to local extreme temperature anomalies. Two data reduction techniques are applied: Legendre polynomial fitting and watershedding. For polynomial fitting a clear
Marczyska, K, Szczepanska, A, Ziemer, C
core  

Seasonal Water "Pump" in the Atmosphere of Mars: Vertical Transport to the Thermosphere

, 2019
We present results of simulations with the Max Planck Institute general circulation model (MPI-MGCM) implementing a hydrological cycle scheme. The simulations reveal a seasonal water "pump" mechanism responsible for the upward transport of water vapor ...
Hartogh, Paul, Medvedev, Alexander S., Rodin, Alexander V., Shaposhnikov, Dmitry S.   +3 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Empirical and modeled synoptic cloud climatology of the Arctic Ocean [PDF]

A daily climatology of the atmospheric circulation of the Arctic and the associated cloud conditions were determined. These are used for comparisons with the variability of general circulation model, generated circulation, and cloud cover for the same ...
Barry, R. G., Crane, R. G.
core   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Extended Kelvin theorem in relativistic magnetohydrodynamics [PDF]

, 2000
We prove the existence of a generalization of Kelvin's circulation theorem in general relativity which is applicable to perfect isentropic magnetohydrodynamic flow. The argument is based on a new version of the Lagrangian for perfect magnetohydrodynamics.
Bekenstein, Jacob D., Oron, Asaf
core   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Tunable current circulation in triangular quantum-dot metastructures

, 2018
Advances in fabrication and control of quantum dots allow the realization of metastructures that may exhibit novel electrical transport phenomena. Here, we investigate the electrical current passing through one such metastructure, a system composed of ...
Chien, Chih-Chun, Di Ventra, Massimiliano, Lai, Chen-Yen, Scheibner, Michael   +3 more
core   +2 more sources