Results 81 to 90 of about 2,926,577 (304)

The upper-atmosphere extension of the ICON general circulation model (version: Ua-icon-1.0) [PDF]

, 2019
How the upper-atmosphere branch of the circulation contributes to and interacts with the circulation of the middle and lower atmosphere is a research area with many open questions.
Baldauf, M., Borchert, S., Reinert, D., Schmidt, H., Zhou, G., Zängl, G.   +5 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

RESULTS OF THE ARC AND ASCENDING AORTA PROSTHETIC REPLACEMENT UNDER DIFFERENT BRAIN PROTECTION CONDITIONS

Российский кардиологический журнал, 2016
Aim. To evaluate the results of prosthetic replacement of ascending aorta and the arc, according to the methods of brain protection.Material and methods. Totally, 63 patients included, 52 (42-60) year old with DeBakey type I chronic dissection.
O. V. Kamenskaya, A. S. Klinkova, A. M. Chernyavskiy, V. V. Lomivorotov, A. M. Karaskov   +4 more
doaj   +1 more source

For Gods\u27 Sake, Copy-edit that Textbook on the Wall [PDF]

, 2014
So, my social streams flooded on Monday with an article from the Denver Business Journal, a weekly Colorado publication with a circulation rate of about 16,000 issues. The internet is an amazingly powerful force for magnification. It can make a rant from
Rudy, John M.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

INFLUENCE OF THE CHRONIC OBSTRUCTIVE PULMONARY DISEASE ON POST-OPERATION COURSE IN CORONARY HEART DISEASE

Российский кардиологический журнал, 2016
Aim. To study the influence of chronic obstructive pulmonary disease (COPD) on post-operation period course in coronary heart disease (CHD) patients after coronary bypass surgery (CBG).Material and methods. Totally, 92 patients included, with CHD.
A. S. Klinkova, O. V. Kamenskaya, A. M. Karaskov   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

IMPACT ОF TARGETED THERAPY WITH VARIOUS TYPES ОF SOLUTIONS ON RENAL FUNCTIONS IN THE PATIENTS UNDERGOING CARDIAC SURGERY

Вестник анестезиологии и реаниматологии, 2017
The article describes the impact of the targeted therapy with colloid and crystalloid infusion solutions on renal function and fluid balance during the surgery and early post-surgery period in the patients who underwent aortocoronary bypass under cardio ...
G. V. Moroz, E. V. Fominski, A. N. Shilova, V. A. Shmyrev, D. G. Shakhin, V. V. Lomivorotov   +5 more
doaj   +1 more source

Southern Annular Mode response to volcanic eruptions: implications for ice core proxies [PDF]

, 2011
Large tropical volcanic eruptions have been observed to have a significant influence on the large-scale circulation patterns of the Northern Hemisphere, through mechanisms related to the radiative effects of the sulfate aerosols resulting from the ...
Krüger, Kirstin, Niemeier, U., Timmreck, C., Toohey, Matthew, Zander, Stefanie   +4 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source