Results 61 to 70 of about 908,418 (219)

RESULTS OF THE ARC AND ASCENDING AORTA PROSTHETIC REPLACEMENT UNDER DIFFERENT BRAIN PROTECTION CONDITIONS

Российский кардиологический журнал, 2016
Aim. To evaluate the results of prosthetic replacement of ascending aorta and the arc, according to the methods of brain protection.Material and methods. Totally, 63 patients included, 52 (42-60) year old with DeBakey type I chronic dissection.
O. V. Kamenskaya, A. S. Klinkova, A. M. Chernyavskiy, V. V. Lomivorotov, A. M. Karaskov   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

INFLUENCE OF THE CHRONIC OBSTRUCTIVE PULMONARY DISEASE ON POST-OPERATION COURSE IN CORONARY HEART DISEASE

Российский кардиологический журнал, 2016
Aim. To study the influence of chronic obstructive pulmonary disease (COPD) on post-operation period course in coronary heart disease (CHD) patients after coronary bypass surgery (CBG).Material and methods. Totally, 92 patients included, with CHD.
A. S. Klinkova, O. V. Kamenskaya, A. M. Karaskov   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

IMPACT ОF TARGETED THERAPY WITH VARIOUS TYPES ОF SOLUTIONS ON RENAL FUNCTIONS IN THE PATIENTS UNDERGOING CARDIAC SURGERY

Вестник анестезиологии и реаниматологии, 2017
The article describes the impact of the targeted therapy with colloid and crystalloid infusion solutions on renal function and fluid balance during the surgery and early post-surgery period in the patients who underwent aortocoronary bypass under cardio ...
G. V. Moroz, E. V. Fominski, A. N. Shilova, V. A. Shmyrev, D. G. Shakhin, V. V. Lomivorotov   +5 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

CEREBRAL OXYMETRY IN HIGH RISK CARDIAC SURGERY: APPLICABILITY AND PROTOCOL OF THE CLINICAL TRIAL

Вестник анестезиологии и реаниматологии, 2018
Cerebral oxymetry is one of the monitoring techniques aimed at the early detection of changes in the brain state. Currently it is being actively introduced into practice, management algorithms for cerebral oxygenation disorders are being developed basing
P. P. Perovskiy, E. V. Fominskiy, V. A. Shmyrev, I. A. Kornilov, V. V. Likhvantsev, V. V. Lomivorotov   +5 more
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Cardiomyocyte overexpression of microRNA-210 mitigates apoptotic cell death induced by doxorubicin

Cardio-Oncology
Background Advancements in cancer diagnostics and treatments have significantly increased patient survival rates. However, these advancements are often accompanied by treatment-induced health issues.
Johan Guthormsen, Mikal Solstad Øiaas, Mido Magdi Allam, Gurdeep Marwarha, Morten Andre Høydal   +4 more
doaj   +1 more source