Results 61 to 70 of about 1,526,491 (315)

Residual circulation trajectories and transit times into the extratropical lowermost stratosphere [PDF]

open access: yes, 2010
Transport into the extratropical lowermost stratosphere (LMS) can be divided into a slow part (time-scale of several months to years) associated with the global-scale stratospheric residual circulation and a fast part (time-scale of days to a few months)
Bönisch, Harald   +3 more
core   +2 more sources

Peak oxygen uptake is a strong prognostic predictor for pulmonary hypertension due to left heart disease

open access: yesBMC Cardiovascular Disorders, 2022
Background Pulmonary hypertension in left heart disease (PH-LHD), which includes combined post- and precapillary PH (Cpc-PH) and isolated postcapillary PH (Ipc-PH), differs significantly in prognosis.
Xiu-Jun Zhong   +13 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

PROSTHESIS OF AORTIC VALVE BY STENTED AND STENTLESS BIOLOGICAL PROSTHESES: INTERMEDIATE ANALYSIS OF RESULTS

open access: yesВестник хирургии имени И.И. Грекова, 2017
OBJECTIVE. The authors assessed an impact of the design of biological prosthesis on efficacy of aortic valve replacement in elderly patients. MATERIAL AND METHODS. Randomized parallel controlled prospective study was carried out.
D. A. Astapov   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

RESULTS OF THE ARC AND ASCENDING AORTA PROSTHETIC REPLACEMENT UNDER DIFFERENT BRAIN PROTECTION CONDITIONS

open access: yesРоссийский кардиологический журнал, 2016
Aim. To evaluate the results of prosthetic replacement of ascending aorta and the arc, according to the methods of brain protection.Material and methods. Totally, 63 patients included, 52 (42-60) year old with DeBakey type I chronic dissection.
O. V. Kamenskaya   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Optimal surface salinity perturbations of the meridional overturning and heat transport in a global ocean general circulation model [PDF]

open access: yes, 2008
Recent observations and modeling studies have stressed the influence of surface salinity perturbations on the North Atlantic circulation over the past few decades.
Nicolas Grima   +17 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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