Results 91 to 100 of about 626,505 (317)

Outcomes of Rate-Control Treatment in Patients With Atrial Fibrillation and Heart Failure- A Nationwide Cohort Study [PDF]

open access: yes, 2018
BACKGROUND: Rate control is now a front-line therapy in the management of atrial fibrillation (AF). However, the survival benefits of different rate-control medications remain controversial, so we assessed the efficacy of rate-control medications in AF ...
유승찬   +8 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Mathematical Simulation of Lost Circulation in Fracture and Its Control

open access: yes, 2021
Lost circulation has been one of the major problems that impede efficient and cost-saving drilling operations. The nature of lost circulation and its control is not yet fully understood.
Hongwei Jiang   +3 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Numerical simulation of transonic circulation control

open access: yes, 2015
Simulations of circulation control via blowing over Coanda surfaces at freestreams up to Mach 0.8 are presented. Validation was conducted against experiments performed at NASA on a 6 percent thick elliptical circulation control aerofoil, which ...
Steijl, R   +3 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Differential Control Rate of Systolic and Diastolic Blood Pressure among Korean Adults with Hypertension: the Sixth Korean National Health and Nutrition Examination Survey, 2013-2015 (KNHANES VI) [PDF]

open access: yes, 2019
BACKGROUND AND OBJECTIVES: Discrepancy in blood pressure (BP) control rate may be owed to different risk factors associated with elevated systolic and diastolic BP (SBP and DBP). METHODS: In a nationally representative survey of Korean population with
김현창, 이호규
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Preserving the Ocean Circulation: Implications for Climate Policy [PDF]

open access: yes
Climate modelers have recognized the possibility of abrupt climate changes caused by a reorganization of the North Atlantic's current pattern (technically known as a thermohaline circulation collapse).
Klaus Keller   +3 more
core  

Computational Modelling of Transonic Circulation Control [PDF]

open access: yes
This Ph.D. thesis focusses upon computational fluid dynamics simulations of circulation control in transonic freestream speeds for applications to unmanned combat air vehicles. The work addresses Coanda shape designs and their effectiveness for transonic
Forster, M
core   +1 more source

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