Results 81 to 90 of about 626,505 (317)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Characterization of Microcrystalline Cellulose after Pretreatment with Low Concentrations of Ionic Liquid-H2O for a Pyrolysis Process

open access: yesBioResources, 2015
Microcrystalline cellulose (MCC) samples pretreated by ionic liquid (ILs)-H2O mixtures were studied for application in a pyrolysis process. A 1-ethyl-3-methylimidazolium methanesulfonate [Emim][MeSO3]-H2O mixture with solid acid catalyst Nafion®NR50 was ...
Qiyu Chen, Takumi Endo, Qingyue Wang
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Aerodynamic Aspects of the Longitudinal Motion of a High-Lift Aircraft Configuration with Circulation Control

open access: yes, 2013
The aim of sub-project C1 of the Collaborative Research Center/Sonderforschungsbereich 880 (SFB 880) is to investigate numerically the flight mechanical characteristics of an aircraft with circulation controlled high-lift devices from an aerodynamic ...
Keller, Dennis, Rudnik, Ralf
core  

Decadal variability of the subtropical gyre and deep meridional overturning circulation of the Indian Ocean [PDF]

open access: yes, 2005
The work presented in this Thesis concerns the large-scale circulation of the Indian Ocean and follows three lines of investigation: (i) decadal variability of the subtropical gyre circulation; (ii) decadal variability of the deep meridional overturning ...
Palmer, M.D., Palmer, Matthew D
core  

Factors Associated with Awareness, Treatment, and Control Rate of Hypertension among Korean Young Adults Aged 30-49 Years [PDF]

open access: yes, 2020
Background and objectives: Hypertension awareness, treatment, and control have been substantially improved in the last decades worldwide, but hypertension management in younger adults is still challenged. We analyzed a nationally representative sample of
김현창, 전용우
core   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Computational Analysis of Circulation Control Airfoils

open access: yes, 2004
Current projections for future aircraft concepts call for stringent requirements on high-lift and low cruise-drag. The purpose of this study is to examine the use of circulation control, through trailing edge blowing, to meet both requirements.
McGowan, Gregory Zar
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

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