Results 41 to 50 of about 641,936 (267)

A See‐Saw of Subduction Rate in the North Pacific Western and Eastern Subtropical Mode Water Formation Areas Induced by the Aleutian Low

Geophysical Research Letters
Subduction of water masses serves as a critical linkage between the surface and subsurface ocean, playing a crucial role in redistributing heat, carbon, and nutrients in the ocean. This process significantly influences global climate and marine ecosystem
Jianing Wang, LingLing Liu, YongFu Lin, JinYi Yu, Fan Wang   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Development of Drilling and Circulation Test System for LWD and Directional Drilling Tool

Shiyou jixie, 2016
The rotary steerable drilling technology has long been the monopoly of foreign company.The lack of the necessary domestic ground test equipment has seriously affected the technology development and industrialization process.In view of this,the drilling ...
Zhang Faming, Wang Zhiming, Wang Dong, Wang Hang, Jian Zhijun, Chen Lei   +5 more
doaj  

Kidney replacement therapy during extracorporeal membrane oxygenation: pathophysiology, technical considerations, and outcomes

Renal Failure
The use of extracorporeal membrane oxygenation has been increasing over time, in part due to the COVID-19 pandemic. Whilst lifesaving, complications that must be managed are also associated with its use.
Michele Petrova Xin Ling Lau, Ryan Ruiyang Ling, Brandon Jin An Ong, Hwa Jin Cho, In-seok Jeong, Tapas Kumar Sahoo, Horng Ruey Chua, Kiran Shekar, Kollengode Ramanathan   +8 more
doaj   +1 more source

Application of quality-controlled sea level height observation at the central East China Sea: Assessment of sea level rise [PDF]

Ocean Science
This study presents a state-of-the-art quality control (QC) process for the sea level height (SLH) time series observed at the Ieodo Ocean Research Station (I-ORS) in the central East China Sea, a unique in situ measurement taken in the open sea for over
T.-B. Jeong, T.-B. Jeong, Y. S. Kim, Y. S. Kim, Y. S. Kim, H. Cha, K.-Y. Jeong, J.-Y. Jeong, J.-H. Lee   +8 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

CLASSIFICATION OF THE LEGAL MODEL OF REAL ESTATE CIRCULATION SYSTEM

Russian Journal of Economics and Law, 2014
Objective: to investigate the principles and role of the legislative definition in the various research methods for modeling the function of legal model of civil rights objects. Methods: abstract-logical and comparative analysis. Results: the analysis of
V. A. Petrushkin
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Projection of ENSO using observation-informed deep learning

Nature Communications
The El Niño-Southern Oscillation (ENSO) profoundly impacts global climate, but its sea surface temperature (SST) variability projected by climate models remains uncertain, with a substantial inter-model spread in 21st-century projections.
Yuchao Zhu, Rong-Hua Zhang, Fan Wang, Wenju Cai, Delei Li, Shoude Guan, Yuanlong Li   +6 more
doaj   +1 more source