Results 71 to 80 of about 641,936 (267)

Supplemental Blood Circulation System in Hematologic Malignancies

open access: yesКлиническая онкогематология, 2014
Neoangiogenesis, i.e. formation of new blood microvessels on the basis of already existing vascular network, is a prerequisite for tumor growth. For years, neoangiogenesis has been considered the only way for delivering oxygen and nutrients to the tumor.
A. A. Vartanyan
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Arctic cyclone activity changes under a warming climate

open access: yesnpj Climate and Atmospheric Science
Arctic cyclones play a crucial role in regional climate and have important linkages to mid-latitude processes. However, their future changes and driving mechanisms remain uncertain.
Yue Chen   +3 more
doaj   +1 more source

Quantifying pulse oximeter accuracy during hypoxemia and severe anemia using an in vitro circulation system. [PDF]

open access: yesJ Clin Monit Comput, 2023
Gylys R   +6 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Simulation of Active Layer Thickness Based on Multi-Source Remote Sensing Data and Integrated Machine Learning Models: A Case Study of the Qinghai-Tibet Plateau

open access: yesRemote Sensing
Permafrost is one of the crucial components of the cryosphere, covering about 25% of the global continental area. The active layer thickness (ALT), as the main site for heat and water exchange between permafrost and the external atmosphere, its changes ...
Guoyu Wang   +8 more
doaj   +1 more source

A new system to prevent SARS-CoV-2 and microorganism air transmission through the air circulation system of endoscopes. [PDF]

open access: yesEndosc Int Open, 2022
Chaussade S   +8 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

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