Results 81 to 90 of about 641,936 (267)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Natural low methoxyl pectin extracted from sunflower heads serves as an efficient biosorbent for lead removal

Scientific Reports
This study demonstrated that extraction temperature serves as a critical parameter for modulating the structural characteristics and Pb2+ adsorption performance of natural low methoxyl pectin derived from sunflower (Helianthus annuus) heads, an abundant ...
Xiaoxia Peng, Qiang Gong, Ruirui Gao, Xiaorui Ci, Zilu Jin, Zhifang Dou, Jianfang Song, Lijuan Song   +7 more
doaj   +1 more source

Development of a valve type semi-closed extracorporeal circulation system. [PDF]

J Artif Organs, 2021
Okumura T, Matsuda K, Fukuoka Y, Dai J, Shiraishi N.   +4 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Off-equatorial winds drive autumn growth rate shifts: contrasting the 2015 and 2023 El Niño events

Geoscience Letters
El Niño represents the most prominent mode of interannual climate variability, with its growth rate critically determining its ultimate intensity. The 2015 and 2023 events were the most recent and two strongest El Niño episodes of the 21st century, yet ...
Panpan Li, Fei Zheng, Linlin Zhang
doaj   +1 more source

Evaluation of a Murine Model for Testing Antimicrobial Implant Materials in the Blood Circulation System. [PDF]

Biomedicines, 2021
Moerke C, Kloss M, Wulf K, Illner S, Kischkel S, Sombetzki M, Grabow N, Reisinger E, Öner A, Ince H.   +9 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Multi-System Urban Waste-Energy Self-Circulation: Design of Urban Self-Circulation System Based on Emergy Analysis. [PDF]

Int J Environ Res Public Health, 2021
Xu X.
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source