Results 11 to 20 of about 1,977 (120)

Neurologic Injury Associated with Rewarming from Hypothermia: Is Mild Hypothermia on Bypass Better than Deep Hypothermic Circulatory Arrest?

Frontiers in Pediatrics, 2016
Many known risk factors for adverse cardiovascular and neurological outcomes in children with congenital heart defects (CHD) are not modifiable, however, the temperature and blood flow during cardiopulmonary bypass (CPB), are two risk factors, which may ...
Utpal S Bhalala, Elumalai Appachi, Muhammad Ali Mumtaz   +2 more
doaj   +2 more sources

Bradykinin induces acute kidney injury after hypothermic circulatory arrest through the repression of the Nrf2-xCT pathway

iScience
Summary: Postoperative acute kidney injury (AKI) is a common complication in patients undergoing deep hypothermic circulatory arrest (HCA); however, its underlying pathogenesis is unclear.
Jinzhang Li, Meili Wang, Maozhou Wang, He Sang, Wei Wang, Ming Gong, Hongjia Zhang   +6 more
doaj   +2 more sources

Emergency Ultra-Deep Hypothermia in Cardiac Arrest Induced by Blood Loss (Experimental Study on Nonhuman Primates)

Общая реаниматология
The survival rate of critically injured individuals with severe blood loss and cardiac arrest is close to zero.Aim. To evaluate the feasibility of using emergency ultra-deep hypothermia (EUDH) in an experimental model of cardiac arrest induced by blood ...
Victor A. Reva, Anastasia R. Samakaeva, Daniil A. Shelukhin, Sergey V. Orlov, Vladimir D. Potemkin, Dmitry V. Bulgin, Galina Y. Gracheva, Alexey V. Shchegolev   +7 more
doaj   +3 more sources

Anestesia para o recém-nascido submetido a cirurgia cardíaca com circulação extracorpórea Anestesia para el recién nacido sometido a cirugía cardiaca con circulación extracorpórea Anesthesia for the newborn submitted to cardiac surgery with cardiopulmonary bypass [PDF]

Revista Brasileira de Anestesiologia, 2005
JUSTIFICATIVA E OBJETIVOS: As doenças congênitas do coração atingem 0,8% dos recém-nascidos (RN) vivos, sendo que muitos necessitam de correção cirúrgica ainda no período neonatal.
Sérgio Bernardo Tenório, Débora O Cumino, Daniela B G Gomes   +2 more
doaj   +2 more sources

Preclinical ¹H MRS Study of a Porcine Model Shows Evidence and Mechanisms for Acute Neuronal Injury in Neonatal Cardiopulmonary Bypass (CPB) Surgery. [PDF]

Magn Reson Med
ABSTRACT Purpose Congenital heart disease affects 1% of US births, with some infants requiring cardiothoracic surgery under cardiopulmonary bypass (CPB). Optimal surgical parameters to minimize neuronal injury are unknown. We used serial 1H MRS in a neonatal CPB porcine model to assess acute neuronal damage and associated injury mechanisms.
Omon A, Gu M, Hurd R, Riemer K, Hanley F, Spielman D.   +5 more
europepmc   +2 more sources

Studies of lipid and carbohydrate metabolism during surface-induced deep hypothermia with circulatory arrest for open-heart surgery

The Japanese Journal of Surgery, 1977
Plasma lipids, blood glucose, plasma insulin (IRI) and serum dopamine-beta-hydroxylase (DBH) were measured in 30 subjects undergoing surface-induced deep hypothermia with circulatory arrest for open-heart surgery. Non-esterified fatty acid (NEFA) in the plasma rapidly increased at the lowest temperature (23 degrees C) reached and other lipids in the ...
Jiro Tsugane, Koichi Inokawa, Masami Morimoto, Hiroshi Shida   +3 more
core   +3 more sources

Early Versus Late Wake-Up Call After Out-Of-Hospital Cardiac Arrest: Protocol for a Multicenter Randomized Comparison Within the Danish Out-of-Hospital Cardiac Arrest (DANOHCA) Trial. [PDF]

Acta Anaesthesiol Scand
ABSTRACT Background Survivors of out‐of‐hospital cardiac arrest (OHCA) who remain comatose after return of spontaneous circulation are routinely sedated and mechanically ventilated during early post‐resuscitation care. Although prolonged sedation has traditionally been considered necessary, contemporary normothermia‐based temperature control allows ...
Grejs AM, Kjaergaard J, Andreasen JB, Rasmussen BS, Hassager C, Meyer MAS, Andersen LPK, Schmidt H, Moelstroem S, Möller S, Torp C, Christensen S, Moeller JE.   +12 more
europepmc   +2 more sources

The risk factors for postoperative cerebral complications in patients with Stanford type a aortic dissection

Journal of Cardiothoracic Surgery, 2019
Background Postoperative cerebral complications (PCC) are common and serious postoperative complications for patients with Stanford type A aortic dissection (AAD).
Yong Lin, Mei-Fang Chen, Hui Zhang, Ruo-Meng Li, Liang-Wan Chen   +4 more
doaj   +1 more source

The human burst suppression electroencephalogram of deep hypothermia [PDF]

, 2017
Objective: Deep hypothermia induces 'burst suppression' (BS), an electroencephalogram pattern with low-voltage 'suppressions' alternating with high-voltage 'bursts'.
Purdon, Patrick L., Akeju, Oluwaseun, Cash, Sydney S., Ching, ShiNung, Pierce, Eric, Brandon Westover, M., Kilbride, Ronan, Kumaraswamy, Vishakhadatta M., Brown, Emery Neal   +8 more
core   +1 more source

Safety of Heparin-Coated Circuits in Primates During Deep Hypothermic Cardiopulmonary Bypass

, 2023
The purpose of this study is to evaluate the biologic impact of heparin-coated circuits without systemic heparinization during deep hypothermia. Baboons (n=6) were placed on a heparin-coated pediatric closed-circuit cardiopulmonary bypass (CPB) system ...
Joseph J. Sistino, Pawel Kwiatkowski, Linda B. Mongero, Robert E. Michler, Arthur Schwartz, Richard Geiman, Charles Marboe   +6 more
core   +1 more source