Results 41 to 50 of about 7,260 (181)

Early Prediction of Neurological Outcome After Cardiac Arrest‐Rationale and Design of the Prospective International Observational EARLY‐NEURO, a STEPCARE Substudy

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 5, May 2026.
ABSTRACT Background Guidelines discourage prediction of neurological outcome in comatose patients within the first 72 h after cardiac arrest. Increasing evidence suggests that patients with the most severe brain injury and those with no or minimal brain injury may be identified before 72 h using novel methods.
Marion Moseby‐Knappe, Erik Westhall, Marjolein Admiraal, Margareta Lang, Helena Levin, Johanna Hästbacka, Marjaana Tiainen, Markus Skrifvars, Gisela Lilja, Janus C. Jacobsen, Alice Lagebrant, Matt Wise, Matti Reinikainen, Paul Young, Manoj Saxena, Simon Schmidbauer, Naomi Hammond, Frances Bass, Ameldina Ceric, Caroline Kamp, Christina Sillassen, Christoph Leithner, Pascal Stammet, Matthias P. Hilty, Pedro D. Wendel‐Garcia, Georg Royl, Tobias Graf, Matt Thomas, Katie Sweet, Stepani Bendel, Joonas Tirkkonen, Annerose Mengel, Maria‐Ioanna Stefanou, Luis Georg Romundstad, Philipp Seidel, Jessica Kåhlin, Jonathan Grip, Jonna Heinonen, Rakesh H. Jadav, Jens Nee, Daniela Nowak, Matthias Hänggi, Johan Undén, Anna Lybeck, Joachim Düring, Martin Kenda, Jesper Johnsson, Niklas Nielsen, Tobias Cronberg   +48 more
wiley   +1 more source

The Novel TRPV1 Agonist ST‐6631 Improves Swallowing Function in Rat Models of Stroke‐Related Dysphagia and Demonstrates Pharmaceutical Advantage Over Capsaicin, by Exhibiting Minimal Pungent and Irritant Properties

Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
ABSTRACT Dysphagia, often associated with neurological disorders such as stroke, not only damages patients' quality of life, like the joy of engaging with meals, but also adversely affects mortality among patients by increasing risks of getting aspiration pneumonia.
Masanori Miyauchi, Hiroyuki Kitano, Mami Kochi, Itaru Natsutani, Yuki Mizukami, Yasuyo Maezawa, Kozo Yoshida, Noboru Iwagaki   +7 more
wiley   +1 more source

AAKD: A standardized and comprehensive acupuncture anesthesia knowledge platform for enhanced recovery after surgery and mechanism

VIEW, Volume 7, Issue 2, April 2026.
Acupuncture anesthesia (AA) is an application of acupuncture innovation in surgical operations, combined with anesthetic techniques, and is a model of integrated Chinese and Western medicine. We proposed the Acupuncture Anesthesia Knowledge Database (AAKD), in which all data have been meticulously curated by field experts and assessed by a multi ...
Ying Wang, Honglian Huang, Chenchen Feng, Xueli Zhang, Weiting Wang, Ziyi Wei, Jing Li, Xintong Yu, Hanzhi Lu, Chunfang Gao, Ke Wang, Jia Zhou   +11 more
wiley   +1 more source

Narrative review of strategies for blood product shelf‐life extension

Transfusion, EarlyView.
Mike Akaraphanth, Jessica Oudakker, Matthew Paulson, Michael Adam Meledeo, Kristin M. Reddoch‐Cardenas, Lusha Xiang, Steven G. Schauer, Todd Getz   +7 more
wiley   +1 more source

Antivirals Targeting Coronavirus RNA‐Dependent RNA Polymerase and Main Protease: From Mechanisms of Action to Outcomes in COVID‐19 Clinical Trials

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
The target sites of COVID‐19 antivirals discussed in the present opinion paper, namely the RNA dependent RNA polymerase Nsp12 and of the main viral protease Nsp5, are indicated by a red star in the overview of the replication cycle of coronavirus SARS‐CoV‐2.
Harald Brüssow
wiley   +1 more source

The ARCH Projects: design and rationale (IAASSG 001) [PDF]

, 2017
OBJECTIVE A number of factors limit the effectiveness of current aortic arch studies in assessing optimal neuroprotection strategies, including insufficient patient numbers, heterogenous definitions of clinical variables, multiple technical strategies ...
Bannon, Paul G., Bavaria, Joseph E., Beyersdorf, Friedhelm, Carrel, Thierry P., Chad Hughes, G., Chen, Edward P., Corvera, Joel S., Coselli, Joseph, Della Corte, Alessandro, Di Bartolomeo, Roberto, Di Eusanio, Marco, Ehrlich, Marek, Elefteriades, John A., Estrera, Anthony, Griepp, Randall B., Haverich, Axel, Hoffman, Andras, Jakob, Heinz, Kazui, Teruhisa, Kouchoukos, Nicholas T., LeMaire, Scott A., Matalanis, George, Misfeld, Martin, Mohr, Friedrich-Wilhelm, Numata, Satoshi, Okita, Yutaka, Oo, Aung, Patel, Himanshu J., Perreas, Konstantinos G., Pochettino, Alberto, Roselli, Eric E., Safi, Hazim J., Shrestha, Malakh, Sinatra, Riccardo, Sun, Li-Zhong, Sundt, Thoralf M., Tabata, Minoru, Tian, David H., Trimarchi, Santi, Underwood, Malcolm J., Wang, Chunsheng, Yan, Tristan D.   +41 more
core  

Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era

Advanced Science, Volume 13, Issue 18, 27 March 2026.
This review provides detailed information on modern cytoprotective strategies for ischemic stroke in the context of recanalization therapies. It derives their rationale based on contemporary knowledge of stroke pathophysiology and discusses the role of advanced imaging approaches as well as concepts for novel clinical trial designs.
Johannes Boltze, Marc Fisher
wiley   +1 more source

Repeated successful surgical rescues of early and delayed multiple ruptures of ventricular septum, right ventricle and aneurysmal left ventricle following massive biventricular infarction [PDF]

, 2006
A 58 year old man underwent 6 surgical interventions for various complications of massive biventricular myocardial infarction over a period of 2 years following acute occlusion of a possibly "hyperdominant" left anterior descending coronary artery. These
Pankaj Kaul, WM Daggett, GM Hutchin's, RG Cummings, JM Swithinbank, J Herlitz, JD Skehan, CA Moore, FF Cox, MJ Rearden, FW Sutherland, TE David, KD Hutchins, K Tanaka, G Schieman, V Mainar, W Blau, JC Madsen, JS Wang, BS Edwards, T Tashiro, T Hirotani, TE David, TE David, MJ Dalrymple-Hay, TA Barker, Gianantonio Nappi, F Musumeci, L Martinelli, N Tabuchi, D Reber, T Takahashi, LD Berrizbeitia, Y Bashir, Y Koh, M Massetti, JL Filiguiera, S Nagamine, C Barriuso, H Ohuchi, A Yamaguchi, MG Cardarelli, E Tatou, B Meyns, FR Waldenberger, SJ Park, C Faber, TE David, DA Killen, MA Deja, L Labrousse, DR Anderson, FF Cox, MJ Dalrymple-Hay, V Menon, B Vajifdar, P Pienvichit, JE Locke, R Anantharaman, R Holzer, WM Dagget, DD Muehrcke, G Mariscalio, JA Goldstein, EM Lee, R Frassani, MH Song, C Blanche, Y Sherer, JC Yuen, R Cartier, HC Suen, A Arbulu, A Kalangos, HC Suen, OY Abu, IN Nuno, JO Fulton, MTT Fukuoka, PE Sokolove, PM Kempen, T Dean, M Ono, KH Kharalambus, I Kusano, JS Tostes, SL Asplund, DD Glower, JG Grieco, JA de Oliveira, KJ Silverman, JC Davila, AS Olearchyk, MJ Anntunes, HD de Boer, AM Cherniavsky, C Guedon, NNGGMGF Luciani, A Kollaar, T Matsuyoshi, T Ivert, J Salas   +101 more
core   +2 more sources

Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?

Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley   +1 more source

The Differential Diagnosis of Coma in the ICU: Hyperacute Postoperative Guillain‐Barré Syndrome—A Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Guillain‐Barré syndrome (GBS) is a rare, immune‐mediated neurological disorder that can be challenging to diagnose in postoperative patients due to atypical manifestations and overlapping conditions. This case report highlights the diagnostic and therapeutic challenges of GBS following vascular surgery. We present the case of a 56‐year‐old man
Miron Tiganas, Abdulrahman Ismaiel, Dan Sebastian Dirzu, Iris Aszalos   +3 more
wiley   +1 more source