ABSTRACT Amiodarone therapy may induce thyroid dysfunction in approximately 20% of patients, either amiodarone‐induced hypothyroidism (AIH) or thyrotoxicosis (AIT). Both situations may occur at any time during treatment or even months to years after drug withdrawal due to tissue storage with slow systemic release.
Daniela M. Soares, Lia Ferreira
wiley +1 more source
Does a reduced glucose intake prevent hyperglycemia in children early after cardiac surgery? a randomized controlled crossover study [PDF]
Introduction: Hyperglycemia in children after cardiac surgery can be treated with intensive insulin therapy, but hypoglycemia is a potential serious side effect.
Betue, C. de +6 more
core +5 more sources
From Pharmaceutical to Biophysical Therapies: New Horizons in Inflammatory Bowel Disease Management
Important limitations exist in the current pharmacological landscape of Inflammatory Bowel Disease (IBD), such as variable response rates and treatment‐limiting adverse effects. In this review, we perform a critical assessment of the current literature on novel multimodal biophysical approaches showing alternative mechanisms of action to, and potential
Benedetta Ricchi +7 more
wiley +1 more source
Cerebral in situ ischemic postconditioning: From bench to bedside and beyond
This review explores the translational potential of in situ ischemic postconditioning in acute ischemic stroke. Preclinical and clinical evidence is summarized to highlight its promise as a neuroprotective strategy in the era of endovascular therapy.
Xiao Jiang +4 more
wiley +1 more source
A hipotermia moderada reduz a infiltração leucocitária na inflamação encefálica induzida [PDF]
Over the last 50 years deep hypothermia (23(0) C) has demonstrated to be an excellent neuroprotective agent in cerebral ischemic injury. Mild hypothermia (31-33(0) C) has proven to have the same neuroprotective properties without the detrimental effects ...
Lapa, Antonio José +3 more
core +3 more sources
Neurological prognostication of outcome in patients in coma after cardiac arrest. [PDF]
Management of coma after cardiac arrest has improved during the past decade, allowing an increasing proportion of patients to survive, thus prognostication has become an integral part of post-resuscitation care.
Oddo, M. +2 more
core +1 more source
Locally induced hypothermia for treatment of acute ischaemic stroke: a physical feasibility study [PDF]
During the treatment of stroke by local intra-arterial thrombolysis (LIT) it is frequently possible to pass the blood clot with a micro-catheter, allowing perfusion of brain tissue distally to the occlusion.
Arnold, M. +8 more
core
Perioperative Hypothermia (33°C) Does Not Increase theOccurrence of Cardiovascular Events in PatientsUndergoing Cerebral Aneurysm SurgeryFindings from the Intraoperative Hypothermia for AneurysmSurgery Trial [PDF]
The IHAST Trial randomized patients undergoing cerebral aneurysm surgery to intraoperative hypothermia or normothermia. Cardiovascular events were prospectively followed until 3-month follow-up and were compared in hypothermic and normothermic ...
Bayman E +6 more
core +1 more source
Neurological Outcomes in Induced Hypothermic States (Post Cardiac Arrest Resuscitation) [PDF]
International studies indicate that induced hypothermia in successful Post Cardiac Arrest Resuscitation improves cerebral perfusion resulting in improved neurological function. Patients undergoing a neurological exam prior to induction of hypothermia may
Bible, Shonna Lee
core +1 more source
Arctic ground squirrel (Spermophilus parryii) and american black bear (Ursus americanus) as models for human cryogenics researches [PDF]
Hibernacija je proces od životne važnosti za organizme koji tijekom ekstremnih zimskih temperatura nemaju mogućnost migracije. Karakteristike svih hibernirajućih organizama su smanjen metabolizam, sniženje tjelesne temperature, povećana upotreba masnoća ...
Kotarski, Lucija
core +2 more sources

