Results 31 to 40 of about 6,960,333 (150)

Economic Evaluation of Prolonged Hypothermic Oxygenated Machine Perfusion Enabling Daytime Liver Transplantation

Artificial Organs, EarlyView.
DHOPE‐PRO enabled daytime liver transplantation with comparable one‐year transplantation‐related costs versus short‐duration DHOPE. Higher perfusion costs were offset by lower surgery‐related costs, suggesting DHOPE‐PRO can improve scheduling logistics without increasing overall hospital costs.
Linda C. Woltjes, Marijke I. Bonnema, Isabel M. A. Brüggenwirth, Veerle A. Lantinga, Christian S. van der Hilst, Vincent E. de Meijer, on behalf of the DHOPE‐PRO Trial Investigators, Marieke T. de Boer, Carlijn I. Buis, Suomi M. G. Fouraschen, Hermien Hartog, Frederik J. H. Hoogwater, Vincent E. de Meijer, Joost M. Klaase, Ruben H. J. de Kleine, Mark Meerdink, Maarten W. Nijkamp, Hans Blokzijl, Frans J. C. Cuperus, Frans van der Heide, Daphne M. Hotho, Frederike G. I. van Vilsteren, A. Boudewijn de Vries, Ilhama F. Abbasova, Johannes P. van den Berg, Jan‐Willem H. L. Boldingh, Meine H. Fernhout, Manon Klaver, Ernesto R. R. Muskiet, Koen M. E. M. Reyntjens, Jaap J. Vos, Miriam Zeillemaker, Isabel M. A. Brüggenwirth, Veerle A. Lantinga, Bianca Lascaris, Adam M. Thorne, Silke B. Bodewes, Sabrina Stimmeder, Ton Lisman, Wouke N. Kuiper, Vivianne E. Veenma, Minou de Bree, Kirsten F. Ma, Roman Kalashnik, Giel M. Van Vliet, Kees Wieriks, Carin Biel, C. Willemijn Binnekamp   +47 more
wiley   +1 more source

Agroecology and Transformative Adaptation to Climate Change

Asia Pacific Viewpoint, EarlyView.
ABSTRACT This paper examines transformative adaptation to climate change through the EFICAS Project (Eco‐Friendly Intensification and Climate‐resilient Agricultural Systems) implemented across 12 upland communities in northern Laos from 2014 to 2020.
Jean‐Christophe Castella
wiley   +1 more source

Clipping of a basilar tip aneurysm using hypothermia and circulatory arrest: a case report.

, 2020
Treatment of complex and giant aneurysms remains challenging despite modern endovascular and microsurgical techniques. We report the first case of microsurgical clipping of a complex basilar tip aneurysm under circulatory arrest and hypothermia performed
Birbilis, T., Gkasdaris, G., Nerntengian, N., Gkasdaris, Grigorios, Nerntengian, Ntenis, Birbilis, Theodosios   +5 more
core   +1 more source

Prehospital whole blood transfusion versus component therapy—A scoping review

Transfusion, EarlyView.
Abstract Background Whole blood has gained a foothold over component therapy in civilian emergency care, especially in emergency departments. In a prehospital setting, whole blood might be the logistically easier alternative compared to component therapy. However, most previous studies have been conducted in the emergency room setting.
Laura Muurinen, Timo Jama, Tom Silfvast, Jouni Lauronen   +3 more
wiley   +1 more source

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Reduced cardiovascular mortality at moderate altitude: a putative role of physical activity and body mass

The Journal of Physiology, EarlyView.
Abstract figure legend Benefits of performing physical exercise at moderate altitude. At moderate altitude, increased resting metabolic rate and physical exertion promote physical fitness and exercise tolerance, whereas hypoxia suppresses appetite and elicits adaptations that increase tissue O2 delivery while augmenting O2‐independent ATP production ...
Robert T. Mallet, Johannes Burtscher, Hannes Gatterer, Katharina Hüfner, Samuel Verges, Tadej Debevec, Martin Burtscher   +6 more
wiley   +1 more source

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

The Role of Deep Hypothermia in Cardiac Surgery

, 2021
Hypothermia is defined as a decrease in body core temperature to below 35 °C. In cardiac surgery, four stages of hypothermia are distinguished: mild, moderate, deep, and profound.
Podsiadło, Paweł, Łukasz Morkisz, Gocoł, Radosław, Bis, Jarosław, Jarosław Bis, Sylweriusz Kosiński, Darocha, Tomasz, Jacek Piątek, Mendrala, Konrad, Tomasz Darocha, Radosław Gocoł, Damian Hudziak, Morkisz, Łukasz, Kosiński, Sylweriusz, Paweł Podsiadło, Piątek, Jacek, Konrad Mendrala, Hudziak, Damian   +17 more
core   +1 more source

An Orthotopic Xenograft Model for Preclinical Evaluation of CAR T Cell Therapy in Glioblastoma

Current Protocols, Volume 6, Issue 11, November 2026.
Abstract Glioblastoma (GBM) is the most lethal primary brain tumor in adults, and despite intensive research efforts, effective therapeutic breakthroughs remain elusive. Consequently, the standard of care has remained largely unchanged for nearly 30 years, underscoring the need for robust preclinical models to evaluate experimental therapies.
Julian Hübner, Rhonda McFleder, Chi Wang Ip, Miriam Alb, Hermann Einsele, Michael Hudecek, Thomas Nerreter   +6 more
wiley   +1 more source

Activation of mitochondrial STAT-3 and reduced mitochondria damage during hypothermia treatment for post-cardiac arrest myocardial dysfunction

, 2017
While therapeutic hypothermia improves the outcomes of individuals in cardiac arrest, the hemodynamic responses and mechanisms which underlie hypothermia-induced cardioprotection are not fully understood. Therefore, we investigated the mechanism by which
Huang, Chien-Hua;Tsai, Min-Shan;Chiang, Chih-Yen;Su, Yu-Jen;Wang, Tzung-Dau;Chang, Wei-Tien;Chen, Huei-Wen;Chen, Wen-Jone, 王宗道;張維典;黃建華;陳文鍾;陳惠文;蔡旼珊   +1 more
core   +1 more source