Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Where in the world are you ? Assessing the importance of circumstance and effort in a world of different mean country incomes and (almost) no migration [PDF]
Suppose that all people in the world are allocated only two characteristics: country where they live and income class within that country. Assume further that there is no migration.
Milanovic, Branko
core
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Boulware state and semiclassical thermodynamics of black holes in a cavity
A black hole, surrounded by a reflecting shell, acts as an effective star-like object with respect to the outer region that leads to vacuum polarization outside, where the quantum fields are in the Boulware state.
C.O. Lousto +9 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Understanding Persistent Food Insecurity: A Paradox of Place and Circumstance [PDF]
Survey data from a USDA-funded multi-state longitudinal project revealed a paradox where rural low-income families from states considered prosperous were persistently more food insecure than similar families from less prosperous states. An examination of
Jean W. Bauer +2 more
core
Exact solution for a fermion in the background of a scalar inversely linear potential
The problem of a fermion subject to a general scalar potential in a two-dimensional world is mapped into a Sturm-Liouville problem for nonzero eigenenergies. The searching for possible bounded solutions is done in the circumstance of power-law potentials.
't Hooft +27 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Criminal associations aimed at committing environmental crimes and aggravating circumstances applicable to the association [PDF]
This report concerns environmental criminal organizations and the system of aggravating circumstances of the associative crime, committed to the commission of crimes against the environment.
Giulio Monferini
doaj
The transmission of fermions of mass m and energy E through an electrostatic potential barrier of rectangular shape (i.e. supporting an infinite electric field), of height U> E + m - due to the many-body nature of the Dirac equation evidentiated by the ...
A. Calogeracos +7 more
core +1 more source

