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The stratification of cirrhosis [PDF]
Cirrhosis is traditionally seen as an irreversible stage of chronic liver disease although its clinical course may last several years. Overall, the clinical management of patients with cirrhosis is based on the observation of clinical events mostly related to complications of portal hypertension.
Maurice, J, Pinzani, M
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Hypotension in Cirrhosis [PDF]
Circulatory and cardiac compromise in cirrhosis has been well studied. The primary pathophysiology stems from portal hypertension, which is induced from an increased resistance to flow secondary to distorted sinusoidal architecture and is further sustained from an increase in portal venous flow.1 Portal hypertension induces both progressive splanchnic ...
Ravi S, Vora, Ram M, Subramanian
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As the treatment of cirrhosis improves, pregnancy in patients with cirrhosis is likely to become more common. Although maternal and fetal mortality is expected to similarly improve, pregnant patients with cirrhosis face unique risks. These include higher rates of spontaneous abortion and prematurity and a potential for life-threatening variceal ...
Jennifer, Tan, Bijal, Surti, Sammy, Saab
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Patients with cirrhosis are at high risk of developing serious infections. Bacterial infections remain the most common cause of morbidity and mortality in these patients. This review is focused on the prevalence of infections in those with cirrhosis, including multidrug-resistant (MDR) pathogens, pathogenesis of infection-related acute-on-chronic liver
Ekpanyapong, Sirina, Reddy, K. Rajender
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Estimated central blood volume in cirrhosis [PDF]
The estimated central blood volume (i.e., blood volume in the heart cavities, lungs and central arterial tree) was determined by multiplying cardiac output by circulatory mean transit time in 19 patients with cirrhosis and compared with sympathetic ...
Ring-Larsen, Helmer +5 more
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Aflatoxin exposure and viral hepatitis in the etiology of liver cirrhosis in the Gambia, West Africa. [PDF]
BACKGROUND: Cirrhosis of the liver is thought to be a major cause of morbidity and mortality in sub-Saharan Africa, but few controlled studies on the etiology of cirrhosis have been conducted in this region.
James J. Goedert +21 more
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Hyponatraemia and cirrhosis [PDF]
Hyponatraemia is a common complication of advanced cirrhosis related to an impairment in the renal capacity for eliminating solute-free water, causing a retention of water that is disproportionate to the retention of sodium, thus leading to a reduction in serum sodium concentration and hypo-osmolality.
Gianotti, Robert J., Cardenas, Andres
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Atrial natriuretic factor (ANF) and renin-aldosterone in volume regulation of patients with cirrhosis [PDF]
The role of the atrial natriuretic factor and of the main counteracting sodium-retaining principle, the renin-aldosterone system, in acute volume regulation of cirrhosis of the liver has been investigated.
Arendt, Rainer M. +5 more
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Hepatitis B viral load and risk for liver cirrhosis and hepatocellular carcinoma in The Gambia, West Africa. [PDF]
The main objectives of this study were to define the occurrence and levels of hepatitis B virus (HBV) DNA in asymptomatic HBV carriers, cirrhosis patients and hepatocellular carcinoma (HCC) cases from The Gambia, and to evaluate the risk for cirrhosis or
Whittle, H +23 more
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CIRRHOSIS WITH PIGMENTATION. [PDF]
The cases of cirrhosis of the liver with pigmentation of the skin or tissues, or of both together, constitute a small but most interesting group. There has been a great deal of speculation as to the etiology of these cases. The purpose of this paper is to present as briefly as possible the history of this form of cirrhosis, the clinical symptoms and ...
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