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Global epidemiology of cirrhosis — aetiology, trends and predictions
Hepatitis C virus (HCV) infection remains the leading cause of global deaths related to cirrhosis, followed by alcohol-associated liver disease. The global burden of cirrhosis associated with non-alcoholic fatty liver disease (NAFLD) has increased ...
Daniel Q Huang +2 more
exaly +2 more sources
Global epidemiology of alcohol-associated cirrhosis and HCC: trends, projections and risk factors
Global alcohol consumption per capita rose from 5.5 litres in 2005 to 6.4 litres in 2016 and is projected to increase further to 7.6 litres in 2030. Currently, Europe has the highest levels of alcohol consumption; however, it is projected to be surpassed
Daniel Q Huang, Rohit Loomba
exaly +2 more sources
Resolving the fibrotic niche of human liver cirrhosis at single-cell level
Liver cirrhosis is a major cause of death worldwide and is characterized by extensive fibrosis. There are currently no effective antifibrotic therapies available.
P. Ramachandran +35 more
exaly +2 more sources
Cirrhosis is a chronic condition resulting from inflammation and fibrosis of the liver. Patients with cirrhosis may have a myriad of physical examination findings that reflect the severity of the underlying liver disease. Although many signs and symptoms related to cirrhosis are nonspecific, such as abdominal pain, nausea, and malaise, some findings ...
Rachel, Wilson, Donna M, Williams
openaire +3 more sources
Background: Patients with cirrhosis and hepatocellular carcinoma (HCC) require extensive care. Personalized education can improve their outcomes. ChatGPT (Generative Pre-trained Transformer), a natural language processing model, has shown potential to ...
Y. Yeo +10 more
semanticscholar +1 more source
Diagnosis and Management of Cirrhosis and Its Complications: A Review.
Importance Cirrhosis affects approximately 2.2 million adults in the US. From 2010 to 2021, the annual age-adjusted mortality of cirrhosis increased from 14.9 per 100 000 to 21.9 per 100 000 people.
E. Tapper, N. Parikh
semanticscholar +1 more source
Computed Tomography Images of Spontaneous Portosystemic Shunt in Liver Cirrhosis
Spontaneous portosystemic shunt (SPSS) refers to collateral vessels that communicate between the portal vein system and systemic circulation. SPSS mainly includes esophageal varices, gastric varices, left gastric vein, recanalized paraumbilical vein ...
Fangfang Yi +7 more
doaj +1 more source
Cirrhosis is defined as the histological development of regenerative nodules surrounded by fibrous bands in response to chronic liver injury, which leads to portal hypertension and end-stage liver disease. Recent advances in the understanding of the natural history and pathophysiology of cirrhosis, and in treatment of its complications, have resulted ...
Detlef, Schuppan, Nezam H, Afdhal
openaire +4 more sources
Portal venous system thrombosis (PVST), a common complication of liver cirrhosis, is closely associated with thrombophilia. To explore the association of homocysteine (Hcy), anticardiolipin antibody (aCL), and anti-β2 glycoprotein I antibody (aβ 2 GPI ...
Le Wang +8 more
doaj +1 more source
Background Endoscopic biliary stenting by endoscopic retrograde cholangiopancreatography (ERCP) is the most common form of palliation for malignant hilar obstruction. However, ERCP in such cases is associated with a risk of cholangitis.
Wen-hui Zhang +7 more
doaj +1 more source

