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Cirrhosis

Medical Clinics of North America, 2022
Cirrhosis is a chronic condition resulting from inflammation and fibrosis of the liver. Patients with cirrhosis may have a myriad of physical examination findings that reflect the severity of the underlying liver disease. Although many signs and symptoms related to cirrhosis are nonspecific, such as abdominal pain, nausea, and malaise, some findings ...
Rachel, Wilson, Donna M, Williams
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Computed Tomography Images of Spontaneous Portosystemic Shunt in Liver Cirrhosis

Canadian Journal of Gastroenterology and Hepatology, 2022
Spontaneous portosystemic shunt (SPSS) refers to collateral vessels that communicate between the portal vein system and systemic circulation. SPSS mainly includes esophageal varices, gastric varices, left gastric vein, recanalized paraumbilical vein ...
Fangfang Yi, Xiaozhong Guo, Qing-Lei Zeng, Benqiang Yang, Yanglan He, Shanshan Yuan, Ankur Arora, Xingshun Qi   +7 more
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Liver cirrhosis [PDF]

Nursing Standard, 2008
Cirrhosis is defined as the histological development of regenerative nodules surrounded by fibrous bands in response to chronic liver injury, which leads to portal hypertension and end-stage liver disease. Recent advances in the understanding of the natural history and pathophysiology of cirrhosis, and in treatment of its complications, have resulted ...
Detlef, Schuppan, Nezam H, Afdhal
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No Association of Homocysteine, Anticardiolipin Antibody, and Anti-β2 Glycoprotein I Antibody With Portal Venous System Thrombosis in Liver Cirrhosis

Clinical and Applied Thrombosis/Hemostasis, 2021
Portal venous system thrombosis (PVST), a common complication of liver cirrhosis, is closely associated with thrombophilia. To explore the association of homocysteine (Hcy), anticardiolipin antibody (aCL), and anti-β2 glycoprotein I antibody (aβ 2 GPI ...
Le Wang, Xiaozhong Guo, Xiangbo Xu, Shixue Xu, Juqiang Han, Ran Wang, Zeqi Guo, Fangfang Yi, Xingshun Qi   +8 more
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CO2 or air cholangiography reduces the risk of post-ERCP cholangitis in patients with Bismuth type IV hilar biliary obstruction

BMC Gastroenterology, 2020
Background Endoscopic biliary stenting by endoscopic retrograde cholangiopancreatography (ERCP) is the most common form of palliation for malignant hilar obstruction. However, ERCP in such cases is associated with a risk of cholangitis.
Wen-hui Zhang, Peng-peng Ding, Lei Liu, Yan-ling Wang, Wen-hui Lai, Jing-jing Han, Jun Han, Han-wei Li   +7 more
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Association of C-type lectin-like receptor 2 and galectin-1 with portal vein system thrombosis in HBV-related liver cirrhosis

Frontiers in Medicine, 2023
Background and aimsHepatitis B virus (HBV) infection is the most common cause of liver cirrhosis. Portal venous system thrombosis (PVST) is a major complication of liver cirrhosis.
Yiyan Zhang, Yiyan Zhang, Xintong Zhang, Xiangbo Xu, Xiangbo Xu, Xiaozhong Guo, Shixue Xu, Shixue Xu, Shaoze Ma, Shaoze Ma, Jihong Chen, Jihong Chen, Xingshun Qi   +12 more
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Serum Mac-2-binding protein glycosylation isomer predicts esophagogastric varices in cirrhotic patients with chronic hepatitis C virus infection treated with IFN-free direct-acting antiviral agent: M2BPGi levels predict varices in SVR patients

Annals of Hepatology, 2020
Introduction and objectives: We examined whether Mac-2-binding protein glycosylation isomer (M2BPGi) levels could be a predictive marker for the presence of esophagogastric varices (EGV) in cirrhotic patients after hepatitis C virus (HCV) eradication ...
Kanako Kikukawa, Sawako Uchida-Kobayashi, Akihiro Tamori, Kanako Yoshida, Kohei Kotani, Hiroyuki Motoyama, Ritsuzo Kozuka, Atsushi Hagihara, Hideki Fujii, Hiroyasu Morikawa, Masaru Enomoto, Yoshiki Murakami, Norifumi Kawada   +12 more
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Identification of novel non-HFE mutations in Chinese patients with hereditary hemochromatosis

Orphanet Journal of Rare Diseases, 2022
Backgrounds Hereditary hemochromatosis (HH) is mainly caused by homozygous p.C282Y mutations in HFE in the Caucasians. We recently reported non-HFE mutations constitute the major cause of HH in Chinese.
Wei Zhang, Yanmeng Li, Anjian Xu, Qin Ouyang, Liyan Wu, Donghu Zhou, Lina Wu, Bei Zhang, Xinyan Zhao, Yu Wang, Xiaoming Wang, Weijia Duan, Qianyi Wang, Hong You, Jian Huang, Xiaojuan Ou, Jidong Jia, China Registry of Genetic/Metabolic Liver Diseases (CR-GMLD) Group   +17 more
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Correlation of genotype and phenotype in 32 patients with hereditary hemochromatosis in China

Orphanet Journal of Rare Diseases, 2021
Background Hereditary hemochromatosis (HH) is widely recognized and clinical manifestations of hemochromatosis-related (HFE-related) HH is well studied in European populations.
Liyan Wu, Wei Zhang, Yanmeng Li, Donghu Zhou, Bei Zhang, Anjian Xu, Zhen Wu, Lina Wu, Shuxiang Li, Xiaoming Wang, Xinyan Zhao, Qianyi Wang, Min Li, Yu Wang, Hong You, Jian Huang, Xiaojuan Ou, Jidong Jia   +17 more
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Association of thromboelastography profile with severity of liver cirrhosis and portal venous system thrombosis

BMC Gastroenterology, 2021
Background and aim Hemostasis profile is often complicated in liver cirrhosis. Thromboelastography is a global viscoelastic test recommended by the current practice guideline and consensus.
Yanglan He, Shanshan Yuan, Xiaozhong Guo, Fangfang Yi, Xiangbo Xu, Yang An, Shixue Xu, Walter Ageno, Xingshun Qi   +8 more
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