Results 11 to 20 of about 326,147 (312)

Clinical characteristics and therapeutic response of immunoglobulin G4-related disease: a retrospective study of 127 Chinese patients

Orphanet Journal of Rare Diseases, 2022
Background and aims Immunoglobulin G4-related disease (IgG4-RD) is a multisystem fibroinflammatory condition. The aim of the present study was to characterize the clinical features and therapeutic response of patients with IgG4-RD and identify risk ...
Wen An, Zhen Wu, Min Li, Haitian Yu, Xinyan Zhao, Xiaoming Wang, Yu Wang, Qianyi Wang, Weijia Duan, Yuanyuan Kong, Hong Ma, Xiaojuan Ou, Hong You, Yanying Liu, Peng Li, Ting Duan, Jidong Jia   +16 more
doaj   +1 more source

Fucosyltransferase 5 Promotes the Proliferative and Migratory Properties of Intrahepatic Cholangiocarcinoma Cells via Regulating Protein Glycosylation Profiles

Clinical Medicine Insights: Oncology, 2023
Background: The incidence of intrahepatic cholangiocarcinoma (ICC) is increasing globally, and its prognosis has not improved substantially in recent years. Understanding the pathogenesis of ICC may provide a theoretical basis for its treatment.
Jingheng Guo, Qian Cheng, Yongjian Li, Lingyu Tian, Delin Ma, Zhao Li, Jie Gao, Jiye Zhu   +7 more
doaj   +1 more source

[Cirrhosis].

Deutsche medizinische Wochenschrift (1946), 2021
The review summarizes the management and therapy of cirrhosis. Special focus is made on the complications of cirrhosis, like variceal bleeding, ascites, renal failure and hepatic encephalopathy.
Alexander, Zipprich, Cristina, Ripoll
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Impact of spider nevus and subcutaneous collateral vessel of chest/abdominal wall on outcomes of liver cirrhosis

Archives of Medical Science, 2019
Introduction Spider nevus and subcutaneous collateral vessel of the chest/abdominal wall are common in liver cirrhosis. This prospective study aimed to evaluate the impact of spider nevus and subcutaneous collateral vessel of the chest/abdominal wall on ...
Hongyu Li, Ran Wang, Nahum Méndez-Sánchez, Ying Peng, Xiaozhong Guo, Xingshun Qi   +5 more
doaj   +1 more source

Extrahepatic Surgery in Cirrhosis Significantly Increases Portal Pressure in Preclinical Animal Models

Frontiers in Physiology, 2021
Background: Liver cirrhosis is a relevant comorbidity with increasing prevalence. Postoperative decompensation and development of complications in patients with cirrhosis remains a frequent clinical problem.
Johannes Chang, Jonathan Meinke, Moritz Geck, Marc Hebest, Nina Böhling, Ramona Dolscheid-Pommerich, Birgit Stoffel-Wagner, Glen Kristiansen, Marcus Overhaus, Leon O. Peyman, Sabine Klein, Frank E. Uschner, Maximilian J. Brol, Tim O. Vilz, Philipp Lingohr, Jörg C. Kalff, Christian Jansen, Christian P. Strassburg, Sven Wehner, Jonel Trebicka, Jonel Trebicka, Michael Praktiknjo   +21 more
doaj   +1 more source

Liver cirrhosis [PDF]

Postgraduate Medical Journal, 1998
Summary Liver fibrosis and its related complications continue to represent a significant worldwide healthcare burden. Over the past decade there has been considerable improvement in our understanding of the cellular mechanisms and pathophysiology underlying hepatic fibrosis.
E J, Williams, J P, Iredale
openaire   +2 more sources

Cell Death and Liver Disease

Gut and Liver, 2020
Cell death is now reclassified into several types based on the mechanisms and morphologic phenotype. Understanding of such classifications offers insights into the pathogenesis of liver disease, as well as diagnostic or therapeutic implications ...
Satoka Aizawa, Gurmehr Brar, Hidekazu Tsukamoto   +2 more
doaj   +1 more source

Serum Liver Fibrosis Markers for Predicting the Presence of Gastroesophageal Varices in Liver Cirrhosis: A Retrospective Cross-Sectional Study

Gastroenterology Research and Practice, 2015
Background and Aims. A retrospective cross-sectional study was conducted to evaluate the role of hyaluronic acid (HA), laminin (LN), amino-terminal propeptide of type III procollagen (PIIINP), and collagen IV (CIV) in predicting the presence of ...
Xingshun Qi, Hongyu Li, Jiang Chen, Chunlian Xia, Ying Peng, Junna Dai, Yue Hou, Han Deng, Jing Li, Xiaozhong Guo   +9 more
doaj   +1 more source

Hepatic stellate cell stearoyl co-A desaturase activates leukotriene B4 receptor 2 - β-catenin cascade to promote liver tumorigenesis

Nature Communications, 2023
Hepatocellular carcinoma (HCC) is the 3rd most deadly malignancy. Activated hepatic stellate cells (aHSC) give rise to cancer-associated fibroblasts in HCC and are considered a potential therapeutic target.
Sonal Sinha, Satoka Aizawa, Yasuhiro Nakano, Alexander Rialdi, Hye Yeon Choi, Rajan Shrestha, Stephanie Q. Pan, Yibu Chen, Meng Li, Audrey Kapelanski-Lamoureux, Gregory Yochum, Linda Sher, Satdarshan Paul Monga, Anthoula Lazaris, Keigo Machida, Michael Karin, Ernesto Guccione, Hidekazu Tsukamoto   +17 more
doaj   +1 more source

Preoperative TIPS prevents the development of postoperative acute-on-chronic liver failure in patients with high CLIF-C AD score

JHEP Reports, 2022
Background & Aims: Acute-on-chronic liver failure (ACLF) is a syndrome associated with organ failure and high short-term mortality. Recently, the role of surgery as a precipitating event for ACLF has been characterised.
Johannes Chang, Pauline Höfer, Nina Böhling, Philipp Lingohr, Steffen Manekeller, Jörg C. Kalff, Jonas Dohmen, Dominik J. Kaczmarek, Christian Jansen, Carsten Meyer, Christian P. Strassburg, Jonel Trebicka, Michael Praktiknjo   +12 more
doaj   +1 more source