Results 11 to 20 of about 303,751 (297)

Fucosyltransferase 5 Promotes the Proliferative and Migratory Properties of Intrahepatic Cholangiocarcinoma Cells via Regulating Protein Glycosylation Profiles

open access: yesClinical Medicine Insights: Oncology, 2023
Background: The incidence of intrahepatic cholangiocarcinoma (ICC) is increasing globally, and its prognosis has not improved substantially in recent years. Understanding the pathogenesis of ICC may provide a theoretical basis for its treatment.
Jingheng Guo   +7 more
doaj   +1 more source

Association of thromboelastography profile with severity of liver cirrhosis and portal venous system thrombosis

open access: yesBMC Gastroenterology, 2021
Background and aim Hemostasis profile is often complicated in liver cirrhosis. Thromboelastography is a global viscoelastic test recommended by the current practice guideline and consensus.
Yanglan He   +8 more
doaj   +1 more source

Clinical characteristics and therapeutic response of immunoglobulin G4-related disease: a retrospective study of 127 Chinese patients

open access: yesOrphanet Journal of Rare Diseases, 2022
Background and aims Immunoglobulin G4-related disease (IgG4-RD) is a multisystem fibroinflammatory condition. The aim of the present study was to characterize the clinical features and therapeutic response of patients with IgG4-RD and identify risk ...
Wen An   +16 more
doaj   +1 more source

Hypotension in Cirrhosis [PDF]

open access: yesClinical Liver Disease, 2019
Circulatory and cardiac compromise in cirrhosis has been well studied. The primary pathophysiology stems from portal hypertension, which is induced from an increased resistance to flow secondary to distorted sinusoidal architecture and is further sustained from an increase in portal venous flow.1 Portal hypertension induces both progressive splanchnic ...
Ravi Vora, Ram Subramanian
openaire   +3 more sources

Impact of spider nevus and subcutaneous collateral vessel of chest/abdominal wall on outcomes of liver cirrhosis

open access: yesArchives of Medical Science, 2019
Introduction Spider nevus and subcutaneous collateral vessel of the chest/abdominal wall are common in liver cirrhosis. This prospective study aimed to evaluate the impact of spider nevus and subcutaneous collateral vessel of the chest/abdominal wall on ...
Hongyu Li   +5 more
doaj   +1 more source

Extrahepatic Surgery in Cirrhosis Significantly Increases Portal Pressure in Preclinical Animal Models

open access: yesFrontiers in Physiology, 2021
Background: Liver cirrhosis is a relevant comorbidity with increasing prevalence. Postoperative decompensation and development of complications in patients with cirrhosis remains a frequent clinical problem.
Johannes Chang   +21 more
doaj   +1 more source

Cell Death and Liver Disease

open access: yesGut and Liver, 2020
Cell death is now reclassified into several types based on the mechanisms and morphologic phenotype. Understanding of such classifications offers insights into the pathogenesis of liver disease, as well as diagnostic or therapeutic implications ...
Satoka Aizawa   +2 more
doaj   +1 more source

Serum Liver Fibrosis Markers for Predicting the Presence of Gastroesophageal Varices in Liver Cirrhosis: A Retrospective Cross-Sectional Study

open access: yesGastroenterology Research and Practice, 2015
Background and Aims. A retrospective cross-sectional study was conducted to evaluate the role of hyaluronic acid (HA), laminin (LN), amino-terminal propeptide of type III procollagen (PIIINP), and collagen IV (CIV) in predicting the presence of ...
Xingshun Qi   +9 more
doaj   +1 more source

Fatigue in Cirrhosis [PDF]

open access: yesJournal of Clinical and Experimental Hepatology, 2022
Fatigue is a common symptom in patients with liver disease and has a significant impact on the health-related quality of life (HR-QoL). Its pathogenesis is poorly understood and is considered multifactorial. The liver is central in the pathogenesis of fatigue because it uniquely regulates much of the production, storage, and release of substrate for ...
Krishnagopal Bhandari, Dharmesh Kapoor
openaire   +3 more sources

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