Results 91 to 100 of about 108,539,901 (307)

cis-eQTL in T2DM-relevant tissues.

open access: yes, 2018
The Venn diagram indicates the numbers of cis-eQTLs in pancreas, liver, adipose subcutaneous and skeletal muscle, and the numbers shared among these tissues.
Tom Hooimeijer (5058752)   +8 more
core   +1 more source

Evaluation of the penetration capacity of bacteria through layers of different face mask types and wearing conditions

open access: yesScientific Reports
The aim of this study was to quantify the number of non-airborne bacteria that can passively penetrate the layers of four mask types (surgical mask, community face mask type 1 (CFM1), biocidal CFM1 and CFM2) and to determine the influence of wearing ...
Alice Kheng   +5 more
doaj   +1 more source

Thy-1 in Integrin Mediated Mechanotransduction

open access: yesFrontiers in Cell and Developmental Biology, 2019
The glycosylphosphatidylinositol (GPI) anchored glycoprotein Thy-1 has been prevalently expressed on the surface of various cell types. The biological function of Thy-1 ranges from T cell activation, cell adhesion, neurite growth, differentiation ...
Ping Hu, Thomas H. Barker
doaj   +1 more source

Radiation induced changes in the structure of CIS-1, 4-polybutadiene [PDF]

open access: yesRadiation Physics and Chemistry (1977), 1979
Abstract The processes occurring during electron irradiation of cis-polybutadiene have been investigated. The concentration of unsaturated bonds decays during irradiation with the formation of intermolecular crosslinks, intramolecular cyclic structures and polyene groups.
openaire   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The economic aspects of the energy sector in CIS countries [PDF]

open access: yes
Final report of a study commissioned by ECFIN to CASE (Centre for Social and Economic Research) This report analyses the macroeconomic aspects of energy sector development in the Commonwealth of Independent States (CIS) countries. It also briefly covers
CASE
core  

Correlations between SmCPS1 promoter polymorphism and tanshinone contents in Salvia miltiorrhiza

open access: yesCzech Journal of Genetics and Plant Breeding, 2018
Copalyl diphosphate synthase 1 (SmCPS1) is the first committed enzyme in tanshinone biosynthesis. The promoter region plays an important role in the transcriptional regulation of genes.
Ying SUN   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A multiple-instance scoring method to predict tissue-specific cis-regulatory motifs and regions [PDF]

open access: yes, 2009
Transcription is the central process of gene regulation. In higher eukaryotes, the transcription of a gene is usually regulated by multiple cis-regulatory regions (CRRs).
Jin Gu
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

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