Results 101 to 110 of about 108,539,901 (307)

Cis-hetero-misogyny online

open access: yes, 2019
This article identifies five genres of anti-queer hate speech found in The Australian’s Facebook comments sections, exposing and analyzing the ways in which such comments are used to derogate cisgender and (often) heterosexual women.
Louise Richardson-Self (14747941)
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Enhancing chemotherapeutic efficacy: Niosome‐encapsulated Dox‐Cis with MUC‐1 aptamer

open access: yesCancer Medicine
Background Cancer remains a formidable global health challenge, currently affecting nearly 20 million individuals worldwide. Due to the absence of universally effective treatments, ongoing research explores diverse strategies to combat this disease ...
Firat Baris Barlas   +9 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

cis-reQTL mapping and SLC45A2 reQTL.

open access: yes, 2016
(A) Outline of the approach for mapping cis-reQTLs (B) QQ plot of the cis-reQTL p-value for all genes tested. Red indicates the top 3 genes discussed in the text and used in subsequent analyses.
Ryosuke Kita (461005)   +1 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

A comparison of ISO11140-1 specified type 4 versus type 5 internal chemical indicators for monitoring sterile packs in steam sterilization processes

open access: yesAntimicrobial Stewardship & Healthcare Epidemiology
Objectives: Six types of chemical indicators (CIs) are specified in ISO11140-1 for monitoring steam sterilization processes (SSP). Types3-6 are “internal” CIs, placed inside packs to assess attainment of sterilizing conditions.
Brian Kirk, Seto Wing Hong
doaj   +1 more source

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