Results 81 to 90 of about 108,539,901 (307)

Discapacidad, trabajo y bienestar

Este trabajo está financiado por el Centro de Investigaciones Sociológicas (CIS)versión ...
Romero Ródenas, María José, Ponce de León Romero, Laura   +1 more
core   +1 more source

Retinol dehydrogenases in retinoid metabolism : studies on a 9-cis/11-cis-retinol dehydrogenase in adult and embryonic tissues

, 2000
Retinoids (vitamin A derivatives) are necessary for normal embryonic development and in the adult, for vision, differentiation of various epithelia, reproduction and in the immune system.
Anna Romert (19528807)
core   +1 more source

Continuous production of cis-1, 4 polyisoprene

, 1971
Bibliography: p. B1-7 .
openaire   +2 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Siklohekzen ve Siklohekzadienlerden Bromosiklitollerin Sentezi

Journal of Ata-Chem
Siklitoller, önemli biyolojik aktiviteleri nedeniyle yoğun şekilde araştırılan bileşiklerdir. Bu çalışmada, siklohekzen, 1,3-siklohekzadien ve 1,4-siklohekzadien temel alınarak yeni bromosiklitol analoglarının sentezi gerçekleştirildi. cis-Hidroksilleme,
Süleyman Göksu, Hasan Seçen, Hülya Çelik   +2 more
doaj   +1 more source

Altered expressions of Notch-1 signaling proteins and beta-catenin in progression of carcinoma in situ into squamous carcinoma of uterine cervix

Indian Journal of Pathology and Microbiology, 2017
Background: Activation of Notch-1 signaling pathway and loss of membranous beta-catenin have been known to play key roles in the progression of uterine cervix cancer and thus this study focused any alteration in the expression patterns for Notch-1, p53 ...
Na-Hye Myong
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Thermolysis of cis,cis,trans-1-phenyl-1,3,5-heptatriene [PDF]

Isomerically pure cis,cis,trans-1-pheny1-1,3,5- heptatriene was prepared and cyclized. Ring closure was followed by a 1,5 hydrogen shift, and the only product observed was 1-phenyl -6-methyl -1,3-cyclohexadiene.
Tilton, Mary Lehman
core   +5 more sources

Effects of short- and long-chain fatty acids on the expression of stearoyl-CoA desaturase and other lipogenic genes in bovine mammary epithelial cells

Animal, 2013
Stearoyl-CoA desaturase (SCD) in the bovine mammary gland introduces a cis-double bond at the Δ9 position in a wide range of fatty acids (FA). Several long-chain polyunsaturated fatty acids (PUFA) inhibit expression of SCD, but information on the effect ...
A.A.A. Jacobs, J. Dijkstra, J.S. Liesman, M.J. VandeHaar, A.L. Lock, A.M. van Vuuren, W.H. Hendriks, J. van Baal   +7 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source