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cis,cis,cis,cis-1,2,3,4,5-Pentakis(hydroxymethyl)cyclopentane
Tetrahedron, 2013All-cis pentamethanolcyclopentane has been obtained in six steps by Diels–Alder condensation of maleic anhydride with (benzyloxymethyl)cyclopenta-2,4-diene, reduction of the anhydride to a diol that was protected as the acetonide. Then, ozonolysis of the double bond, followed by reduction led to a cis-diol.
Pujol, Adeline +2 more
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GREAT improves functional interpretation of cis-regulatory regions
Nature Biotechnology, 2010We developed the Genomic Regions Enrichment of Annotations Tool (GREAT) to analyze the functional significance of cis-regulatory regions identified by localized measurements of DNA binding events across an entire genome.
Cory Y. McLean +7 more
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The inversion of cis-transoid-cis- and cis-cisoid-cis-perhydroanthracene
Tetrahedron Letters, 1982Abstract The factor responsible for the difference between the inversion barriers of cis-transoid-cis- and cis-cisoid-cis -perhydroanthracene were explored by molecular mechanics.
P. Vanhee +3 more
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cis,cis,cis,cis-1,2,3,4,5-Pentakis(hydroxymethyl)cyclopentane
The Journal of Organic Chemistry, 1985Synthese du compose du titre par addition de Diels Alder de l'anhydride maleique avec le benzyloxymethyl ...
Laren M. Tolbert +2 more
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Enantioselective syntheses of cis, syn, cis- and cis, anti, cis-linear triquinanes
Tetrahedron: Asymmetry, 2008Enantioselective syntheses of both cis, syn, cis- and cis, anti, cis-linear triquinanes, starting from the readily available (S)-campholenaldehyde, employing an RCM reaction-based cyclopentannulation strategy, are described.
Srikrishna, Adusumilli, Beeraiah, Baire
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Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses
Science, 2019Sparing T cells from inhibition Programmed cell death 1 (PD-1) is an inhibitory receptor that normally keeps T cell immune responses in check. Immunotherapy targeting PD-1 has proven successful for certain types of cancer, but it remains unclear how PD-1
D. Sugiura +6 more
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All-cis-retinal and 7-cis,9-cis,11-cis-retinal1
Tetrahedron Letters, 1988Abstract A modified 15 + 5 route led to 7- cis ,9- cis ,11- cis -retinonitrile in high selectivity and also a lesser amount of all- cis -retinonitrile. DIBAL reduction gave the corresponding retinal isomers. The absorption maximum 287nm of all- cis -retinal reveals the distorted nature of the chromophore.
Achla Trehan, R.S.H. Liu
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ChemInform Abstract: CIS,CIS,CIS,CIS‐1,2,3,4,5‐PENTAKIS(HYDROXYMETHYL)CYCLOPENTANE
Chemischer Informationsdienst, 1985AbstractDie Synthese des im Titel genannten Cyclopentans (V) gelingt durch Diels‐Alder‐Addition.
L. M. TOLBERT +2 more
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A cis,trans,cis,cis-[4.5.5.5]Fenestrane Derivative
Acta Crystallographica Section C Crystal Structure Communications, 1996The title compound, rel-(1R,4R,7S,10R)-7-(tert-butyldimethylsilyloxy)tetracyclo [5.4.1.04,12.010,12]dodecan-2-one, C18H30O2Si, has been prepared and its structure determined. The geometry of the central C(C)4 substructure of the fenestrane skeleton shows a considerable distortion from an ideal tetrahedral arrangement towards planarity. Values of 127.0
M. Thommen, R. Keese, M. Förtsch
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A Substituted cis,trans,cis,cis-[4.5.5.5]Fenestrene
Acta Crystallographica Section C Crystal Structure Communications, 1996The title compound, rel-(1S,4R,7R,9S-tetracyclo- [5.4.1.0 4,12 .0 9,12 ]dodec-10-enyl-l-acetic acid, C 14 H 18 O 2 , has been prepared and its structure elucidated. The geometry of the central C(C)4 substructure shows a considerable distortion from an ideal tetrahedral arrangement towards planarity, with two opposite bond angles of of 119.2(2) and 134 ...
J. Wang, M. Thommen, R. Keese
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