Synergism between dipyridamole and cisplatin in human breast cancer cells in vitro
Química Nova, 2003 Cisplatin is very effective in the treatment of metastatic breast cancer. However, the development of cellular resistance is a serious problem in cisplatin chemotherapy.
Janice R. Perussi +3 more
doaj +1 more source
NPRL2 sensitizes human non-small cell lung cancer (NSCLC) cells to cisplatin treatment by regulating key components in the DNA repair pathway. [PDF]
PLoS ONE, 2010 NPRL2, one of the tumor suppressor genes residing in a 120-kb homozygous deletion region of human chromosome band 3p21.3, has a high degree of amino acid sequence homology with the nitrogen permease regulator 2 (NPR2) yeast gene, and mutations of NPRL2 ...
Gitanjali Jayachandran +4 more
doaj +1 more source
Cycloaurated GoId (III) complexes- Possible alternatives to cisplatin? [PDF]
, 2009 The serendipitous discovery of the anti-tumour activity of cisplatin [cis-PtCI₂(NH₃)₂] in 1969 has led to increased interest in the development of new metal-based anti-cancer drugs.
Henderson, William, Kilpin, Kelly Joan
core +1 more source
Association of ABCB1, 5-HT3B receptor and CYP2D6 genetic polymorphisms with ondansetron and metoclopramide antiemetic response in Indonesian cancer patients treated with highly emetogenic chemotherapy. [PDF]
, 2011 Our study shows that in Indonesian cancer patients treated with highly cytostatic emetogenic, carriership of the CTG haplotype of the ABCB1 gene is related to an increased risk of delayed chemotherapy-induced nausea and ...
Baak-Pablo, Renee F +8 more
core +2 more sources
Advanced Biology, EarlyView.Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer +8 more
wiley +1 more source
Gemcitabine and carboplatin in intensively pretreated patients with metastatic breast cancer [PDF]
, 2007 Background: Patients with metastatic breast cancer (MBC) are increasingly exposed to anthracyclines and taxanes either during treatment of primary breast cancer or during initial therapy of metastatic disease.
Fasching, P. A. +13 more
core +1 more source
Beyond the Beam: Exploring Charged Particle Nanoprinting
Advanced Functional Materials, EarlyView.Charged particle nanoprinting using electrons and ions is highly advanced, offering great potential for research and industry. However, challenges in precursor design and process optimization persist, but also offer great opportunities to drive nanofabrication innovations.
Nicolas Paul Jochmann +2 more
wiley +1 more source
Breast Cancer Research, 2019 Background Chemotherapy is a standard therapeutic regimen to treat triple-negative breast cancer (TNBC); however, chemotherapy alone does not result in significant improvement and often leads to drug resistance in patients.
Jung Ok Lee +12 more
doaj +1 more source
Prolactin and its receptor as therapeutic targets in glioblastoma multiforme [PDF]
, 2019 Although prolactin (PRL) and its receptor (PRLR) have been detected in glioblastoma multiforme (GBM), their role in its pathogenesis remains unclear. Our aim was to explore their contribution in GBM pathogenesis.
Abt, Araceli +13 more
core +1 more source
Metal Nanoclusters for Cancer Imaging and Treatment
Advanced Functional Materials, EarlyView.This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu +5 more
wiley +1 more source