Results 241 to 250 of about 416,036 (340)

Polysaccharide‐Coated ETCA Nanoparticles Containing the Methoxyl Substituted Indole‐Thiazole Derivative and Their Antiproliferative Activity in Breast Cancer Cells

Journal of Applied Polymer Science, EarlyView.
ABSTRACT Indole and thiazole derivatives have garnered significant attention due to their potent antitumor activities. Encapsulation of such derivatives into polymeric nanoparticles offers several advantages, including improved molecular stability and targeted delivery to tumor sites, thereby enhancing their antineoplastic potential.
José Cleberson Santos Soares, Iago Dillion Lima Cavalcanti, Iranildo José da Cruz‐Filho, Mariane Cajubá de Britto Lira Nogueira, Maria do Carmo Alves de Lima   +4 more
wiley   +1 more source

Cisplatin resistance in head and neck squamous cell carcinoma is linked to DNA damage response and cell cycle arrest transcriptomics rather than poor drug uptake. [PDF]

Cancer Drug Resist
Sandu K, Warta R, Biswas U, Zhang W, Michl P, Herold-Mende C, Weiss J, Theile D.   +7 more
europepmc   +1 more source

Two cases of resected mediastinal malignant germ cell tumors following cisplatin, vinblastine, and bleomycin combination chemotherapy.

, 1987
Akira Hayashibe, Yutaka Nishiwaki, Tetsuro Kodama, Yoshiyuki Nishiyama, Heiichi Yano, Hideki Kudo, Ryoichi Honda, Mitsunori Hino, Yoshimasa Inoue, Takaki Zaisho, Harumi Oshima, Tomoki Kitaya, Tomoji Matsuyama, Fumio Nagasaki, Seiichi Tamai   +14 more
openalex   +2 more sources

Synthesis of BODIPY‐Linked N‐Heterocyclic Carbene Metal Complexes for Cancer Chemotheranostics and Catalysis Applications

Chemistry – An Asian Journal, EarlyView.
A simple and efficient design strategy for the synthesis of BODIPY‐linked N‐Heterocyclic Carbene Metal Complexes (Ag, Cu, Ni, Pd) is developed. Fluorescent BODIPY‐silver carbene complex is useful for cellular imaging and shows chemotheraputic anti‐cancer activity.
Shraddha SP Yadav, Ananda Guha Majumdar, Manish Ramesh Shingole, Seemita Banerjee, Mahesh Subramanian, Rohit Singh Chauhan, Soumyaditya Mula   +6 more
wiley   +1 more source

The molecular mechanisms of mitochondrial dynamics and mitophagy and their complex association with cancer drug resistance. [PDF]

J Transl Med
Zhao Z, Ren Y, Yuan M, Liu G, Sun J.
europepmc   +1 more source

Functional effects of maternal exposure to a single dose of cisplatin on the brain of the offspring in the rat

, 1989
Tomoko Fujii, Yasuo Kusama
openalex   +1 more source

The Stem Cell Transcription Factor OCT4 Silences Target DNA Methyltransferase 1 to Strengthen DNA Damage Response in Cisplatin‐Treated Gastric Cancer Cells

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT OCT4 plays a crucial role in the DNA damage response(DDR) mechanism, whereas cisplatin (CDDP) acts as an anti‐tumor agent by inducing DDR. This study aimed to investigate the role of OCT4 in regulating DNA methyltransferase 1 (DNMT1) in CDDP‐treated gastric cancer (GC).
Zhengzheng Yan, Xiaoqian Bu, Haixia Chen, Chongren Ren, Ji Li, Yongjie Wu, Jun Xing   +6 more
wiley   +1 more source

The synergistic action of HDAC inhibitor with cisplatin impedes survival and proliferation of drug-tolerant persister in gastric and liver cancer cells. [PDF]

Clin Epigenetics
Singh A, Natu A, Anthony F, Muthu H, Khade B, Smoot DT, Ashktorab H, Gupta S.   +7 more
europepmc   +1 more source

The effect of cisplatin dacarbazine vindesine therapy for progressive stage malignant melanoma.

, 1989
Naoya Yamazaki, Hideya Sasaki, K Hayasaka, Kazuyuki Ishihara   +3 more
openalex   +2 more sources

Pharmacokinetics of teicoplanin in paediatric patients—A systematic review of current literature

British Journal of Clinical Pharmacology, EarlyView.
Background and Objective Teicoplanin is commonly used in children to treat gram‐positive infections and is sometimes used off‐label prophylactically in surgical or paediatric oncology settings. The pharmacokinetics (PK) of teicoplanin in children exhibit considerable variability, such as in critically ill children or those with renal impairment.
Noa E. Wijnen, Daan J. Touw, Kim Klein, Gertjan J. L. Kaspers, Paola Mian   +4 more
wiley   +1 more source