Results 221 to 230 of about 366,991 (303)

Rhenium Complexes as Antimicrobial Agents

Helvetica Chimica Acta, EarlyView.
Rhenium complexes are stepping into the fight against superbugs. Our new review explores how these metallic complexes could inspire the next generation of antimicrobial therapies. ABSTRACT The escalating crisis of antimicrobial resistance (AMR) necessitates the exploration of unconventional therapeutic scaffolds.
Fabio Zobi, Gozde Demirci, Marija Rasic
wiley   +1 more source

Nitric oxide-dependent stabilization of vimentin confers chemoresistance in ovarian cancer. [PDF]

Mol Ther Nucleic Acids
Melone G, Bayraktar R, Zhao H, Hynes SO, Kaar F, Freegrove A, Deng J, Baseviciene A, Uzair I, Martinez KO, Guzman-Rojas L, Chervo MF, Li M, Qian W, Zhou J, Phillips A, Zambo KDA, Nikolos F, Chan KS, Thomas C, Francis L, Chang JC.   +21 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Mechanistic study of the role of emodin in targeting and inhibiting the Rap1 signaling pathway to regulate epithelial-mesenchymal transition and reverse cisplatin resistance in hepatocellular carcinoma. [PDF]

Transl Cancer Res
Zhang R, Jiao Y, Wang S, Wang L, Leng Y, Xiong Z, Yang M.   +6 more
europepmc   +1 more source

Systemic anti‐cancer therapy associated with the occurrence of peripheral neurotoxicity and, specifically, peripheral neuropathy

International Journal of Cancer, EarlyView.
What's New? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins, Lynn R. Gauthier, Blair H. Smith, Lesley Colvin   +3 more
wiley   +1 more source

Dynamic changes of the immune microenvironment in ovarian cancer following neoadjuvant chemotherapy. [PDF]

Cell Death Discov
Wu M, Lv F, Jin Y, Wang S, Meng L, Tong J, Zou R.   +6 more
europepmc   +1 more source

Risk of childhood and adolescent, and young adult cancer in offspring of men with testicular cancer: A Danish nationwide study

International Journal of Cancer, EarlyView.
What's New? Testicular germ cell cancer (TC), the most common solid tumor among young men in Western countries, has survival rates exceeding 95 percent, allowing most survivors to pursue fatherhood. Concerns remain, however, about cancer risk in offspring, given potential mutagenic effects incurred during treatment for TC.
Mikkel Bandak, Susanne Rosthøj, Gitte Lerche Aalborg, Jakob Lauritsen, Aleksander Giwercman, Hege Sagstuen Haugnes, Gedske Daugaard, Allan Jensen   +7 more
wiley   +1 more source

Nivolumab plus gemcitabine-cisplatin for unresectable or metastatic urothelial carcinoma: health-related quality-of-life analyses from the phase III CheckMate 901 trial. [PDF]

ESMO Open
Bedke J, van der Heijden MS, Sonpavde G, Galsky MD, Liao W, Shi L, Blum SI, Mitra S, Patel MY, Powles T.   +9 more
europepmc   +1 more source

Indirect Comparison of Neoadjuvant Treatment Strategies for Muscle‐Invasive Bladder Cancer: ddMVAC and Perioperative Durvalumab‐Gemcitabine‐Cisplatin Versus Gemcitabine‐Cisplatin: A Systematic Review and Network Meta‐Analysis of Randomised Controlled Trials

International Journal of Cancer, EarlyView.
Optimizing neoadjuvant therapy for muscle‐invasive bladder cancer patients who are eligible for cisplatin remains difficult, owing particularly to high toxicity and recurrence rates. This meta‐analysis compared dose‐dense methotrexate, vinblastine, doxorubicin, and cisplatin (ddMVAC) against durvalumab plus gemcitabine‐cisplatin (D‐GC) and GC alone ...
Maurin Helen Mangold, Gloria Baumann, Victoria Luise Simone Wieland, Nicolas Carl, Luisa Vivienne Renner, Alexander Studier‐Fischer, Hanna Menold, Stefanie Zschäbitz, Frederik Wessels, Niklas Westhoff, Maurice Stephan Michel, Karl‐Friedrich Kowalewski, Caelán Max Haney‐Aubert   +12 more
wiley   +1 more source

Comparative Analysis of the Transcriptomic Response to Cisplatin in Drug-Sensitive and Drug-Resistant Testicular Germ Cell Tumors. [PDF]

Cancers (Basel)
Khan MW, Shokry D, Boyd RI, Singh R, Spinella MJ.   +4 more
europepmc   +1 more source