Results 241 to 250 of about 256,231 (309)

The USP19-DnaJC7 Axis Stabilizes p53 in Cisplatin-Treated Epithelial Ovarian Cancer. [PDF]

Cells
Min Y, Kim D, Park HB, Choi HS, Hwang S, Baek KH.   +5 more
europepmc   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

Interdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione, Ana Talamillo, Juan M. Falcón‐Pérez   +2 more
wiley   +1 more source

Impact of European Association of Urology Combination and Platinum Eligibility on Real-World Treatment Sequences and Survival in Japanese Patients With Metastatic Urothelial Carcinoma. [PDF]

Int J Urol
Kawahara T, Nagumo Y, Tanuma K, Hamada K, Yamaguchi A, Nitta S, Shiga M, Ikeda A, Hoshi A, Kandori S, Nishiyama H.   +10 more
europepmc   +1 more source

New Hydrazone Derivatives Featuring Isatin and Piperazine Moieties: Synthesis, Cytotoxicity Evaluation, and Molecular Modeling Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT In this study, ten novel compounds (IPH1–IPH10) were designed by integrating three pharmacophores (isatin, piperazine, and hydrazone) commonly found in the molecular structures of anticancer agents. The target molecules were obtained by the reaction of in‐house prepared 4‐(4‐(pyridin/pyrimidin‐2‐yl)piperazin‐1‐yl)benzohydrazide with various ...
Semiha Köprü, Münevver Baran, Miyase Gözde Gündüz, Şengül Dilem Doğan   +3 more
wiley   +1 more source

Loss of proximal tubule lactate dehydrogenase A exacerbates nephrotoxic acute kidney injury through metabolic dysregulation. [PDF]

Am J Physiol Renal Physiol
Lu Y, Zmijewska AA, Zhang Y, Osis G, Cheung MD, Wilson L, Jiang Y, Vejendla S, Traylor A, Barnes S, George JF, Agarwal A.   +11 more
europepmc   +1 more source

Redox-triggered USP18 confers cisplatin resistance in ovarian cancer by selectively activating a non-canonical FSP1-dependent ferroptosis escape pathway. [PDF]

Redox Biol
Zhao Z, Ge G, Gong M, Liu Y, Ma L, Zhang D, Sun L, Song Y.   +7 more
europepmc   +1 more source

Cisplatin resistance in oral squamous cell carcinoma: mechanisms, reversal strategies, and emerging technologies. [PDF]

Front Physiol
Shi Y, Liao W, Bai G, Chen B.
europepmc   +1 more source

Disrupting SOX2 self-association and condensate formation to overcome chemotherapeutic drug resistance in lung squamous cell carcinoma. [PDF]

Signal Transduct Target Ther
Wang J, Wen Y, Huang S, Liu Y, Dong X, Liu H, Guo Z, Li J, Zhou C, Wang H, Zhang L, Wang Z, Li W, Yao H.   +13 more
europepmc   +1 more source

The role of oxidative stress and antioxidant therapy in cisplatin neurotoxicity: preclinical evidence in the last decade. [PDF]

Arch Toxicol
Dos Santos NAG, Dos Santos JM, Dos Santos AC.   +2 more
europepmc   +1 more source

Potential Benefit of Sodium-Glucose Cotransporter 2-Inhibitors in Cisplatin-Associated Nephrotoxicity Among Patients With Cancer Having Diabetes Mellitus. [PDF]

Kidney Int Rep
Cintrón-García JJ, Patel M, Andersen CR, Page V, Workeneh B, Mandayam S, Al-Dallal R, Abudayyeh A, Mamlouk O.   +8 more
europepmc   +1 more source