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The Diagnosis and Treatment of Lung Cancer: Methods, evidence and guidance [PDF]
, 2005 Belchamber, C.A. +1 more
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Single-cell insights into cisplatin resistance mechanisms in bladder cancer tumor microenvironment. [PDF]
J Biol ChemXu L +5 more
europepmc +1 more source
In Vitro Anti-Glioblastoma Activity of a Novel Pt(IV)-Ganoderic Acid A Conjugate. [PDF]
Int J Mol SciGaiaschi L +7 more
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Essays in Biochemistry, 1999
Cisplatin is a widely used anti-cancer drug that is exceptionally effective against testicular cancer. trans-DDP, the geometric isomer of cisplatin, is ineffective as a chemotherapeutic agent. The anti-tumour activity of cisplatin is generally attributed to its formation of DNA adducts, both intrastrand and interstrand crosslinks, which induce ...
E E, Trimmer, J M, Essigmann
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Cisplatin is a widely used anti-cancer drug that is exceptionally effective against testicular cancer. trans-DDP, the geometric isomer of cisplatin, is ineffective as a chemotherapeutic agent. The anti-tumour activity of cisplatin is generally attributed to its formation of DNA adducts, both intrastrand and interstrand crosslinks, which induce ...
E E, Trimmer, J M, Essigmann
openaire +2 more sources
Toxicology Letters, 1989
Cisplatin is used widely in the treatment of a large number of carcinomas. The clinical use of cisplatin, however, can be complicated by myelotoxicity, ototoxicity and intestinal toxicity; we review briefly cisplatin nephrotoxicity. The principal route of its excretion is via the kidney, and accumulation of cisplatin in the renal cortex has been ...
J P, Fillastre, G, Raguenez-Viotte
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Cisplatin is used widely in the treatment of a large number of carcinomas. The clinical use of cisplatin, however, can be complicated by myelotoxicity, ototoxicity and intestinal toxicity; we review briefly cisplatin nephrotoxicity. The principal route of its excretion is via the kidney, and accumulation of cisplatin in the renal cortex has been ...
J P, Fillastre, G, Raguenez-Viotte
openaire +2 more sources
Seminars in Nephrology, 2003
Cisplatin remains a major antineoplastic drug for the treatment of solid tumors. Its chief dose-limiting side effect is nephrotoxicity, which evolves slowly and predictably after initial and repeated exposure. The kidney accumulates cisplatin to a higher degree than other organs perhaps via mediated transport.
Istvan, Arany, Robert L, Safirstein
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Cisplatin remains a major antineoplastic drug for the treatment of solid tumors. Its chief dose-limiting side effect is nephrotoxicity, which evolves slowly and predictably after initial and repeated exposure. The kidney accumulates cisplatin to a higher degree than other organs perhaps via mediated transport.
Istvan, Arany, Robert L, Safirstein
openaire +2 more sources