Results 21 to 30 of about 276,154 (298)

Identification of genes associated with cisplatin resistance in human oral squamous cell carcinoma cell line

BMC Cancer, 2006
Background Cisplatin is widely used for chemotherapy of head and neck squamous cell carcinoma. However, details of the molecular mechanism responsible for cisplatin resistance are still unclear.
Zhang Ping, Zhang Zhiyuan, Zhou Xiaojian, Qiu Weiliu, Chen Fangan, Chen Wantao   +5 more
doaj   +1 more source

The Effect of Bone Marrow Transplantation on Oocyte-Granulosa Cell Interaction and Follicular Development of Cisplatin-Induced Ovarian Failure in Rat

Journal of Stem Cell Research and Tissue Engineering, 2021
Introduction: Chemotherapy has cytotoxic effect that induces follicular damage and abnormal folliculogenesis leads to ovarian failure. Two crucial   growth factors in abnormal folliculogenesis, Growth Differentiation Factor-9 (GDF-9) and Kit-Ligand, will
hendi hendarto
doaj   +1 more source

Gemcitabine plus carboplatin versus mitomycin, ifosfamide, and cisplatin in patients with stage IIIB or IV non-small-cell lung cancer: a phase III randomized study of the London Lung Cancer Group [PDF]

, 2005
Purpose: This phase III randomized trial compared two chemotherapy regimens, gemcitabine plus carboplatin and mitomycin, ifosfamide, and cisplatin, in chemotherapy-naive patients with advanced non-small-cell lung cancer (NSCLC).
Harper, P.G., Johnson, P.W.M., Harper, P. G., Qian, W., Rudd, R. M., Spiro, S.G., Gregory, W. M., Hatton, M., Eisen, T. G., James, L.E., Rankin, E. M., Johnson, P. W. M., Rankin, E.M., Spiro, S. G., Rudd, R.M., Lee, S. M., Littler, J. A. H., Lee, S.M., Littler, J.A.H., Eisen, T.G., Martin, W.M.C., Gregory, W.M., James, L. E., Gower, N. H., Martin, W. M. C., Gower, N.H.   +25 more
core   +1 more source

Transforming Growth Factor Alpha Stimulation of Mucosal Tissue Cultures from Head and Neck Squamous Cell Carcinoma Patients Increases Chemoresistance to Cisplatin [PDF]

, 2010
The monoclonal epidermal growth factor receptor ( EGFR) antibody cetuximab (Erbitux(TM)) was recently approved by the European Medicines Agency for the treatment of recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC) in combination ...
Baumeister, Philipp, Ulrich Harréus, Schwenk-Zieger, Sabina, Maximilian Reiter, Philipp Baumeister, Reiter, Maximilian, Sabina Schwenk-Zieger, Harreus, Ulrich   +7 more
core   +1 more source

Time-restricted feeding protects against cisplatin-induced acute kidney injury in mice [PDF]

Kidney Research and Clinical Practice
Background Time-restricted feeding (TRF), devoid of calorie restriction, is acknowledged for promoting metabolic health and mitigating various chronic metabolic diseases.
Kyu Won Jang, Young Suk Kim, Min Jeong Kim, Seo Rin Kim, Dong Won Lee, Soo Bong Lee, Il Young Kim   +6 more
doaj   +1 more source

Protein flexibility is key to cisplatin crosslinking in calmodulin [PDF]

, 2012
Chemical crosslinking in combination with Fourier transform ion cyclotron resonance mass spectrometry (FTICR MS) has significant potential for studying protein structures and proteinprotein interactions.
Römer, Rudolf A., Sadler, P. J., Zhao, Yao, (Researcher in chemistry), O'Connor, Peter B., Jimenez-Roldan, J. Emilio, Wells, Stephen A., Li, Huilin   +6 more
core   +1 more source

Roles of Reactive Oxygen Species and Autophagy in the Pathogenesis of Cisplatin-Induced Acute Kidney Injury

, 2022
Cisplatin-induced acute kidney injury (AKI) is the main factor restraining the clinical application of cisplatin. The AKI is associated with high mortality and morbidity, but no effective pharmacological treatment is available at present.
Sawamura Haruka, 1000050242110, Yoshikawa Sayuri, Ikeda Yuka, Matsuda Satoru, つじ あい, まつだ さとる, Taniguchi Kurumi, 辻 愛, Tsuji Ai, 松田 覚   +10 more
core   +1 more source

Cisplatin Nanocapsules

, 2005
Cisplatin nanocapsules represent a novel lipid formulation of the anticancer drug cis-diamminedichloroplatinum(II), in which nanoprecipitates of cisplatin are covered by a phospholipid bilayer coat consisting of an equimolar mixture of phosphatidylcholine and phosphatidylserine.
de Kroon, A.I.P.M., Staffhorst, R.W.H.M., de Kruijff, B., Burger, K.N.J.   +3 more
openaire   +4 more sources

Upregulations of P2X3 and ASIC3 involve in hyperalgesia induced by cisplatin administration in rats [PDF]

, 2010
名古屋大学Nagoya University博士(医学)The role of ion channels expressed in sensory neurons on mechanical and thermal hyperalgesia was examined in a rat model of cisplatin-induced peripheral neuropathy.
Suzuki, Shigeyuki, Ozaki, Noriyuki, Hori, Kiyomi, Sugiura, Yasuo   +3 more
core   +1 more source

Are serial CA 19-9 kinetics helpful in predicting survival in patients with advanced or metastatic pancreatic cancer treated with gemcitabine and cisplatin? [PDF]

, 2003
Background: Serial kinetics of serum CA 19-9 levels have been reported to reflect response and survival in patients with pancreatic cancer undergoing surgery, radiotherapy, and chemotherapy.
Stoffregen, C., Stemmler, J., Wilkowski, R., Garbrecht, M., Schalhorn, A., Lamerz, Rolf, Stieber, P., Szymala, A. M., Schermuly, M. M., Heinemann, Volker, Helmberger, T., Niebler, K.   +11 more
core   +1 more source