Results 11 to 20 of about 202,668 (261)
Glutamine protects against cisplatin-induced nephrotoxicity by decreasing cisplatin accumulation
Journal of Pharmacological Sciences, 2015 Cisplatin is a chemotherapeutic drug but induces acute kidney injury (AKI). Cisplatin-induced AKI depends on several signaling pathways leading to apoptosis in tubular epithelial cells.
Hyun-Jung Kim +9 more
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1-Hydroxy-8-methoxy-anthraquinon reverses cisplatin resistance by inhibiting 6PGD in cancer cells
Open Life Sciences, 2019 Targeting 6-phosphogluconate dehydrogenase (6PGD) can inhibit cancer cell proliferation and tumor growth. However, the relationship between 6PGD and cisplatin resistance still needs further study.
Zhang Huamin +4 more
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BMC Cancer, 2006 Background Cisplatin is widely used for chemotherapy of head and neck squamous cell carcinoma. However, details of the molecular mechanism responsible for cisplatin resistance are still unclear.
Zhang Ping +5 more
doaj +1 more source
Journal of Stem Cell Research and Tissue Engineering, 2021 Introduction: Chemotherapy has cytotoxic effect that induces follicular damage and abnormal folliculogenesis leads to ovarian failure. Two crucial growth factors in abnormal folliculogenesis, Growth Differentiation Factor-9 (GDF-9) and Kit-Ligand, will
hendi hendarto
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Cisplatin decreases HOXA13 and alphaVBeta3 integrin levels in the uterus
Taiwanese Journal of Obstetrics & Gynecology, 2021 Objective: To examine the effects of cisplatin on uterine histology and implantation molecules and the possible protective role of recombinant Klotho administration on uterine histology and uterine receptivity in mice exposed to cisplatin.
Mustafa Albayrak +6 more
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Time-restricted feeding protects against cisplatin-induced acute kidney injury in mice [PDF]
Kidney Research and Clinical PracticeBackground Time-restricted feeding (TRF), devoid of calorie restriction, is acknowledged for promoting metabolic health and mitigating various chronic metabolic diseases.
Kyu Won Jang +6 more
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, 2005 Cisplatin nanocapsules represent a novel lipid formulation of the anticancer drug cis-diamminedichloroplatinum(II), in which nanoprecipitates of cisplatin are covered by a phospholipid bilayer coat consisting of an equimolar mixture of phosphatidylcholine and phosphatidylserine.
de Kroon, A.I.P.M. +3 more
openaire +4 more sources
Redox Biology, 2016 Cisplatin-induced ototoxicity remains a primary dose-limiting adverse effect of this highly effective anticancer drug. The clinical utility of cisplatin could be enhanced if the signaling pathways that regulate the toxic side-effects are delineated.
Samson Jamesdaniel +2 more
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Fatal Overdosage with Cisplatin [PDF]
Journal of Analytical Toxicology, 2004 This paper presents a case of fatal overdosage due to an accidental massive administration (750 mg instead of 170 mg) of cisplatin, an anticancer agent, to a 63-year-old patient suffering from lymphoma. Platinum was measured in various postmortem samples by means of inductively coupled plasma mass spectrometry. Heart and peripheral blood concentrations
Charlier, Corinne +3 more
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Targeting HNRNPU to overcome cisplatin resistance in bladder cancer
Molecular Cancer, 2022 Purpose The overall response of cisplatin-based chemotherapy in bladder urothelial carcinoma (BUC) remains unsatisfactory due to the complex pathological subtypes, genomic difference, and drug resistance.
Zhen-duo Shi +18 more
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