Results 101 to 110 of about 43,016 (203)

Combination of Citalopram and Nortriptyline in Treatment of Moderate to Severe Major Depression: A Double-blind, Placebo- controlled Trial [PDF]

Iranian Journal of Psychiatry, 2006
Objective: Depression is a major health problem, which is not only underrecognized and undertreated, but is also associated with significant morbidity and mortality.
Mohammad Reza Mohammadi, Abbas Ali Nasehi, Nastaran Habibi, Firoozeh Raisi   +3 more
doaj   +1 more source

Actionable Pharmacogenomics and Essential Medicines: An Analysis of WHO and African Lists for Safer and Efficacious Drug Use

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1371-1381, May 2026.
The World Health Organization Model Essential Medicines List and African national essential medicines lists (EMLs) detail drugs intended to be consistently available within national health systems, thereby supporting clinicians and pharmacists in making evidence‐based treatment decisions.
Tinashe A. Mazhindu, Mohamed Nagy, David Twesigomwe, Gaye Agesa, Janine Scholefield, Collen Masimirembwa   +5 more
wiley   +1 more source

Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. [PDF]

, 2019
Mood disorders are highly prevalent and are the leading cause of disability worldwide. The neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have ...
Dulawa, Stephanie C, Janowsky, David S
core  

The Burden of Adverse Drug Reactions in Africa in the Context of Pharmacogenetics‐Based Clinical Guidelines

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1382-1390, May 2026.
Genetic variation has a significant impact on patients' response to medicines. Variations in important pharmacogenes have been evaluated in several studies and consequently led to international guidelines from clinical pharmacogenomics consortia. However, there are limited examples of these being implemented across the African continent despite the ...
Janine Scholefield, Tinashe A. Mazhindu, Mohamed Nagy, David Twesigomwe, Gaye Agesa, Collen Masimirembwa   +5 more
wiley   +1 more source

Out‐of‐Pocket Costs and Antidepressant Adherence in Head and Neck Cancer Survivors

Psycho-Oncology, Volume 35, Issue 5, May 2026.
ABSTRACT Background Head and neck cancer (HNC) survivors have a high burden of depression, yet real‐world antidepressant adherence and the role of patient out‐of‐pocket (OOP) costs in this population remain poorly characterized. Methods We analyzed a retrospective cohort of US adults with HNC and a new antidepressant prescription in Merative MarketScan
Gennaro Di Tosto, Neil K. Mehta, Christopher W. Noel, Ann Scheck McAlearney, Lauren E. Miller   +4 more
wiley   +1 more source

A Review of the Role of Melatonin in Irritable Bowel Syndrome [PDF]

, 2014
Irritable bowel syndrome (IBS) is a troubling disease experienced worldwide. The presentation of symptoms varies from patient to patient, and current prescription treatments can be inadequate in resolving symptoms.
Brinn, Nicole R., Gandhi, Mona A.
core   +1 more source

Prescribing Practice of Citalopram and Escitalopram in Older Adults Following the 2014 MHRA Guidance of Associated QTc Prolongation: A Clinical Audit

BJPsych Open
Aims Citalopram and escitalopram are commonly used serotonin-specific reuptake inhibitors (SSRIs) for the treatment of depression and anxiety. These medications are known to cause corrected QT interval (QTc) prolongation, with risks of further ...
Shreyan Kar, Aparna Prasanna
doaj   +1 more source

Influence of tobacco smoke on the pharmacokinetics of citalopram and its enantiomers [PDF]

, 2012
The purpose of this study was to evaluate the influence of tobacco smoke on the pharmacokinetics of citalopram (CIT) and desmethylcitalopram (DCIT) and its enantiomers on an animal model.
Florek, Ewa, Jawień, Wojciech, Kulza, Maksymilian, Majcherczyk, Jagoda, Piekoszewski, Wojciech, Seńczuk-Przybyłowska, Monika   +5 more
core  

Depression, Anxiety, and Quality of Life in Breast Cancer Patients with Depression Receiving Citalopram and Supportive Group Psychotherapy: A Six-month Longitudinal Study

Journal of Mazandaran University of Medical Sciences, 2019
Background and purpose: Depression is a common psychiatric disorder in patients with breast cancer. This study was performed to follow-up breast cancer patients with depression receiving citalopram and group psychotherapy for six months.
Novin Nikbakhsh, Sussan Moudi, Farimah Mohammadian Amiri, Maede Niazifar, Ali Bijani   +4 more
doaj  

Sertraline, citalopram and paroxetine in lactation: passage into breastmilk and infant exposure

Frontiers in Pharmacology
ObjectivesThis study aimed to investigate the plasma and breastmilk concentrations for sertraline, citalopram and paroxetine for assessment of the Milk/Plasma (M/P) ratio and Absolute Infant Dose (AID), and to determine actual infant drug exposure ...
Daphne Den Besten-Bertholee, Daan J. Touw, Daan J. Touw, Elvera A. Damer, Paola Mian, Paola Mian, Peter G. J. Ter Horst   +6 more
doaj   +1 more source