Results 31 to 40 of about 1,031,008 (313)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Collective Impact Partnerships: The Data to Action Hourglass Model
Interdisciplinary Journal of Partnership Studies, 2022 Models are needed to guide positive health care and social transformation using real-world data, particularly in an era of data-driven science and accountability.
Karen Monsen +6 more
doaj +1 more source
Arts in Cities - Cities in Arts
Articulo – revue de sciences humaines, 2017 The presence of cities in art and the presence of art in cities are two fields which have often been studied separately, be it by different disciplines (history, geography, sociology, etc.) or by various approaches within a single discipline (cultural geography or urban geography for example).
Molina, Géraldine, Guinard, Pauline
openaire +3 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
City Festivals and Festival Cities [PDF]
, 2020 This chapter discusses the role of city festivals in shaping and re-imagining urban space. There has been increased interest in festivals among decision-makers and marketers as vehicles for cultural profiling, regeneration, and social inclusion. The chapter views space as inseparable from economic and social structures and practices which govern urban ...
openaire +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
, 1972 Pamphlet for the Model Cities: Facets of Community Development for Little Rock, Arkansas. Published by the National Model Cities Community Development Directors Association, National League of Cities in Washington, D. C.
National Model Cities Community Development Directors Association
core +1 more source
“BIOPOLIS”: Biopolicy for Greener and More Livable Cities
Cadmus, 2013 Urban centers are the engines which must bear the brunt of required changes to meet climate change mitigation goals, whilst continuing to provide social and economic opportunities.
“BIOPOLIS”: Biopolicy for Greener and More Livable Cities
doaj