Results 41 to 50 of about 1,390,912 (292)

City Festivals and Festival Cities [PDF]

, 2020
This chapter discusses the role of city festivals in shaping and re-imagining urban space. There has been increased interest in festivals among decision-makers and marketers as vehicles for cultural profiling, regeneration, and social inclusion. The chapter views space as inseparable from economic and social structures and practices which govern urban ...
openaire   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Comparing Postoperative Outcomes of Isolated Anterior Cruciate Ligament Reconstruction and the “Terrible Triad” Anterior Cruciate Ligament Reconstruction With Medial Meniscus Ramp and Lateral Meniscus Root Repairs

Orthopaedic Journal of Sports Medicine
Background: A new “terrible triad” has been reported to be an anterior cruciate ligament (ACL) tear with a concomitant medial meniscus ramp tear and lateral meniscus root tear.
Evan P. Shoemaker BA, Luke V. Tollefson BS, Nicholas I. Kennedy MD, Rebecca Stone McGaver MS, ATC, Morgan Homan DO, Kayla J. Sieffert BA, Ayush D. Shah BA, Corey A. Wulf MD, Christopher M. Larson MD, Brian P. Bjerke MD, Robert F. LaPrade MD, PhD   +10 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Isolated Proximal Tibiofibular Joint Reconstruction With Semitendinosus Tendon Autograft in a Collegiate Athlete

Video Journal of Sports Medicine
Background: Proximal tibiofibular joint (PTFJ) instability is a rare and often underrecognized cause of lateral knee pain and dysfunction, most commonly presenting as anterolateral subluxation of the fibular head after trauma.
Romir Patel MD, Luke V. Tollefson BS, Benjiman J. Wilebski MD, ATC, Dustin R. Lee MD, Matthew T. Rasmussen MD, Robert F. LaPrade MD, PhD   +5 more
doaj   +1 more source

Excision of Femoral Heterotopic Ossification and Lysis of Adhesions After Medial Collateral Ligament Reconstruction

Arthroscopy Techniques
Heterotopic ossification (HO) and arthrofibrosis are known complications after medial collateral ligament (MCL) reconstruction and other arthroscopic procedures.
Grace Guerin, B.S., Taidhgin Keel, B.S., Luke V. Tollefson, B.S., Evan P. Shoemaker, B.A., Erik L. Slette, M.D., Nathan J. Jacobson, M.D., Robert F. LaPrade, M.D., Ph.D.   +6 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Regional hippocampal thinning and gyrification abnormalities and associated cognition in children with prenatal alcohol exposure

Journal of Neurodevelopmental Disorders
Background Prenatal alcohol exposure (PAE) impacts hippocampal structure and function, contributing to deficits in memory and decision-making in affected individuals.
Blake A. Gimbel, Jeffrey R. Wozniak, Bryon A. Mueller, Kent A. Tuominen, Abigail M. Ernst, Mary E. Anthony, Erik de Water, the CIFASD, Donovan J. Roediger   +8 more
doaj   +1 more source

The City of the Senses, the Senses in the City

, 2022
Urban-oriented sensory analysis has a long tradition within the social sciences. However, in communication and cultural studies research, the sensorial orientation is still incipient. This publication is part of an ongoing call by Passeio, the platform for the study of art and urban culture of the Communication and Society Research Centre, for an ...
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