Results 41 to 50 of about 2,967,272 (314)

Collective Impact Partnerships: The Data to Action Hourglass Model

Interdisciplinary Journal of Partnership Studies, 2022
Models are needed to guide positive health care and social transformation using real-world data, particularly in an era of data-driven science and accountability.
Karen Monsen, Diana Drake, Wendy Looman, Barbara Peterson, Maria Ruud, Sheila Smith, Daniel Pesut   +6 more
doaj   +1 more source

Factors Influencing Cities' Publishing Efficiency [PDF]

, 2018
Recently, a vast number of scientific publications have been produced in cities in emerging countries. It has long been observed that the publication output of Beijing has exceeded that of any other city in the world, including such leading centres of ...
Csomos, Gyorgy
core   +2 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Comparing Postoperative Outcomes of Isolated Anterior Cruciate Ligament Reconstruction and the “Terrible Triad” Anterior Cruciate Ligament Reconstruction With Medial Meniscus Ramp and Lateral Meniscus Root Repairs

Orthopaedic Journal of Sports Medicine
Background: A new “terrible triad” has been reported to be an anterior cruciate ligament (ACL) tear with a concomitant medial meniscus ramp tear and lateral meniscus root tear.
Evan P. Shoemaker BA, Luke V. Tollefson BS, Nicholas I. Kennedy MD, Rebecca Stone McGaver MS, ATC, Morgan Homan DO, Kayla J. Sieffert BA, Ayush D. Shah BA, Corey A. Wulf MD, Christopher M. Larson MD, Brian P. Bjerke MD, Robert F. LaPrade MD, PhD   +10 more
doaj   +1 more source

Excision of Femoral Heterotopic Ossification and Lysis of Adhesions After Medial Collateral Ligament Reconstruction

Arthroscopy Techniques
Heterotopic ossification (HO) and arthrofibrosis are known complications after medial collateral ligament (MCL) reconstruction and other arthroscopic procedures.
Grace Guerin, B.S., Taidhgin Keel, B.S., Luke V. Tollefson, B.S., Evan P. Shoemaker, B.A., Erik L. Slette, M.D., Nathan J. Jacobson, M.D., Robert F. LaPrade, M.D., Ph.D.   +6 more
doaj   +1 more source

The influence of the revitalization of former industrial urban areas on new urban and tourism spaces: case studies of Manchester and Lyon [PDF]

, 2012
The purpose of this article is the identification of changes to urban and tourism space due to the revitalization of the industrial wastelands in selected cities of Western Europe.
Kazimierczak, Jarosław
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Regional hippocampal thinning and gyrification abnormalities and associated cognition in children with prenatal alcohol exposure

Journal of Neurodevelopmental Disorders
Background Prenatal alcohol exposure (PAE) impacts hippocampal structure and function, contributing to deficits in memory and decision-making in affected individuals.
Blake A. Gimbel, Jeffrey R. Wozniak, Bryon A. Mueller, Kent A. Tuominen, Abigail M. Ernst, Mary E. Anthony, Erik de Water, the CIFASD, Donovan J. Roediger   +8 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source