Results 41 to 50 of about 3,585,619 (339)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Filling the Third Circle with Interdisciplinary Lesson Planning: A Case Study of Pre-Service Teachers

open access: yesJournal of Human Sciences and Extension, 2022
The three-circle model of agricultural education focuses on the importance of in-class instruction, supervised agricultural experiences, and FFA involvement.
Garrett Steede   +2 more
doaj   +1 more source

Smart & sustainable cities [PDF]

open access: yes, 2013
The University of Strathclyde is creating a new Institute for Future Cities that aims to improve the quality of human life across the world through innovative research that enables cities to be understood in new ways, and innovative approaches to be ...
Bellingham, Richard, Purshouse, Nicholas
core  

Efficient energy management for the internet of things in smart cities [PDF]

open access: yes, 2017
The drastic increase in urbanization over the past few years requires sustainable, efficient, and smart solutions for transportation, governance, environment, quality of life, and so on.
Anpalagan, Alagan   +4 more
core   +1 more source

City of Dog [PDF]

open access: yesJournal of Urban History, 2020
To be fully human in the Greco-Roman world was to be a member of a city. This is unsurprising as cities were the building blocks of Greek and Roman culture and society. The urban landscape of post-Roman Western Europe looked dramatically different, with smaller, less economically diverse cities which played a smaller role in administration.
openaire   +3 more sources

Trade and Cities [PDF]

open access: yesSSRN Electronic Journal, 2012
Many developing countries display remarkably high degrees of urban concentration that are incommensurate with their levels of urbanization. The cost of excessively high levels of urban concentration can be very high in terms of overpopulation, congestion, and productivity growth.
Karayalcin, Cem, Yilmazkuday, Hakan
openaire   +5 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

Using the RE-AIM Framework to Evaluate Disaster Recovery Videos

open access: yesJournal of Human Sciences and Extension, 2022
Natural disasters both increase and cause financial challenges for survivors. Crisis support reduces negative outcomes such as financial stress, yet survivors are often unaware or unable to access available services. Aiming to innovatively improve access
Sarah Cronin   +2 more
doaj   +1 more source

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