Results 11 to 20 of about 14,194 (220)

Citocinas en la salud del adulto mayor

Investigar y Aprender, 2016
El envejecimiento esta asociado con un incremento en los niveles de citocinas catabolicas y con la declinacion de la inmunidad humoral. Estas citocinas desempenan un papel importante en el estado de salud de los adultos mayores, regulando la respuesta inmunologica ante estimulos estresantes tanto fisicos como psicologicos.
Jasmina M. Correa Alfaro, Tatiana M. Echavarría Hernández   +1 more
openaire   +3 more sources

Cytokine inhibitors and pain control Inibidores de citocinas e controle da dor

Revista Brasileira de Reumatologia, 2007
The authors describe the evidences supporting the role of cytokines in experimental pain, discussing possible approaches for pain control using cytokine-targeting therapies.Os autores fazem uma revisão sobre evidências que demonstram o papel de citocinas
Waldiceu A. Verri Jr., Thiago M. Cunha, Stephen Poole, Sérgio H. Ferreira, Fernando Q. Cunha   +4 more
doaj   +2 more sources

AVALIAÇÃO DE CITOCINAS NA FIBROSE HEPÁTICA INDUZIDA EM RATOS PELA LIGADURA DO DUCTO BILIAR

Revista UniVap, 2015
A fibrose hepática é uma doença causada por uma grande variedade de doenças crônicas que afetam o fígado após diferentes agressões, cujo único tratamento é o transplante de fígado.
Juliana Saraiva Freitas, Amanda Birindeli Alkmin, Luciana Barros Sant´Anna, Maria Angélica Gargione Cardoso   +3 more
doaj   +2 more sources

Cytokine transcriptome profiling in acute experimental canine atopic dermatitis skin lesions after IL‐31 inhibition with lokivetmab

Veterinary Dermatology, Volume 34, Issue 4, Page 327-338, August 2023., 2023
Background – The caninised monoclonal antibody lokivetmab (LKV), directed at interleukin (IL)‐31, is very effective at controlling pruritus in most dogs with atopic dermatitis (AD). However, evidence exists that IL‐31 is not required for the induction of acute allergic skin inflammation, which might explain why this treatment is less efficacious in ...
Chie Tamamoto‐Mochizuki, Natalie Crawford, Jordan M. Eder, Andrea J. Gonzales, Thierry Olivry   +4 more
wiley   +1 more source

The effect of a mixed cannabidiol and cannabidiolic acid based oil on client‐owned dogs with atopic dermatitis

Veterinary Dermatology, Volume 33, Issue 4, Page 329-e77, August 2022., 2022
Background– Cannabidiol (CBD) and cannabidiolic acid (CBDA) are reported to have antinociceptive, immunomodulatory and anti‐inflammatory actions. Objectives – To determine if CBD/CBDA is an effective therapy for canine atopic dermatitis (cAD). Conclusions and clinical relevance – Cannabidiol/CBDA as an adjunct therapy decreased pruritus, and not skin ...
Melissa Loewinger, Joseph J. Wakshlag, Daniel Bowden, Jeanine Peters‐Kennedy, Andrew Rosenberg   +4 more
wiley   +1 more source

Altered plasma cytokines in dogs with atopic dermatitis

Veterinary Dermatology, Volume 33, Issue 2, Page 131-e38, April 2022., 2022
Background – Canine (Canis lupus familiaris) atopic dermatitis (AD) shares similar clinical signs to human AD. The abnormal immune response of AD is orchestrated by T lymphocytes, and may include variable involvement of cytokines, Regulatory T (Treg) cells, eosinophils, mast cells and other immune components.
Hamutal Mazrier, Linda J. Vogelnest, Rosanne M. Taylor, Peter Williamson   +3 more
wiley   +1 more source

Onset and duration of action of lokivetmab in a canine model of IL‐31 induced pruritus

Veterinary Dermatology, Volume 32, Issue 6, Page 681-e182, December 2021., 2021
Onset of antipruritic action of lokivetmab in dogs. Laboratory‐bred beagle dogs were dosed subcutaneously with either placebo or lokivetmab at 2.0 mg/kg on Day (D) 0. Approximately 2.5 h post‐dosing, pruritus was induced using canine interleukin (IL)‐31. Animals were observed for pruritic behaviours for a total of 2 h (3–5 h post‐treatment with placebo
Timothy J. Fleck, Lori R. Norris, Sean Mahabir, Rodney R. Walters, Olivier Martinon, Steven A. Dunham, Andrea J. Gonzales   +6 more
wiley   +1 more source

Immunopathogenesis and immunotherapy of Culicoides hypersensitivity in horses: an update

Veterinary Dermatology, Volume 32, Issue 6, Page 579-e156, December 2021., 2021
Culicoides hypersensitivity (CH) is a strongly pruritic dermatitis of horses, characterised histologically by mixed perivascular to diffuse cellular infiltrates of mononuclear cells and eosinophils, and caused by helper T cell (Th)2, immunoglobulin (Ig)E‐mediated reactions to antigens present in the saliva of biting Culicoides midges.
Eliane Marti, Ella N. Novotny, Iva Cvitas, Anja Ziegler, A. Douglas Wilson, Sigurbjörg Torsteinsdottir, Antonia Fettelschoss‐Gabriel, Sigridur Jonsdottir   +7 more
wiley   +1 more source

Immunopathogenesis of the feline atopic syndrome

Veterinary Dermatology, Volume 32, Issue 1, Page 13-e4, February 2021., 2021
Résumé Contexte Les maladies félines supposées d’origine allergique avec des phénotypes cliniques semblables, peuvent avoir de nombreuses pathogénies différentes sous jacentes. Le phénotype clinque, l’étiologie précise et l’immunopathogénie sous jacente doivent tous être considérés si des avancées veulent être faites dans ces domaines négligés de la ...
Richard Halliwell, Frane Banovic, Ralf S. Mueller, Thierry Olivry   +3 more
wiley   +1 more source

COVID-19: Compreendendo a “tempestade de citocinas”

Research, Society and Development, 2021
O SARS-CoV-2 espalhou-se rapidamente pela China e logo recebeu atenção mundial, levando a Organização Mundial da Saúde (OMS) a declarar, em 30 de janeiro de 2020, a infecção pelo SARS-CoV-2 como emergência de saúde pública de interesse internacional.
Raffaela Neves Mont'Alverne Napoleão, Ana Beatriz Gomes Santiago, Mariella Almeida Moreira, Sônia Leite da Silva, Silvia Fernandes Ribeiro da Silva   +4 more
openaire   +2 more sources