Results 21 to 30 of about 551 (132)
Organoid technology was used to create a preclinical model for evaluation of hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal metastases from colorectal cancer. Current HIPEC regimens were tested and a novel rational treatment combination of mitomycin C with inhibitors of ATR was investigated.
I. Ubink +13 more
wiley +1 more source
Modelo de detección de anticuerpos neutralizantes contra IFN-β mediante citometría de flujo
Introducción. El interferón beta (IFN-β) se usa para tratar la forma recaída-remisión de la esclerosis múltiple. Sin embargo, el uso de proteínas recombinantes como medicamentos puede generar la producción de anticuerpos, disminuyendo así la efectividad ...
Juan Carlos Villa-Camacho +2 more
doaj +1 more source
Dendritic cells (DCs) play a key role in the induction of peripherally induced regulatory T cells (Tregs) under homeostatic and inflammatory conditions. This study demonstrates that inhibins modulate the induction of Tregs from naïve T cells in the periphery through promoting DC maturation and function.
Marisol de la Fuente‐Granada +4 more
wiley +1 more source
Recently, a subpopulation of tumor cells, called cancer stem cells (CSC), has been characterized, and these have emerged as a major topic in cancer research. CSC are proposed to repair DNA damage more efficiently than the rest of tumor cells, resisting chemotherapy or radiotherapy and causing clinical recurrence and metastasis.
Heriberto Abraham Valencia-González +4 more
wiley +1 more source
El sistema genético de Paspalum lilloi (Poaceae), especie endémica de las Cataratas del Iguazú
Introducción y objetivos: Paspalum lilloi (Poaceae) es una especie diploide y endémica de las Cataratas del Iguazú y áreas circundantes, cuya biología reproductiva y área de distribución geográfica actual es desconocida. Los objetivos de este trabajo son
Anna Verena Reutemann +5 more
doaj +3 more sources
ABSTRACT Nanocellulose is being increasingly used in biomedical applications because of its biocompatibility, mechanical robustness, tunable surface chemistry, and adjustable rheology. This review evaluates recent strategies for engineering cellulose nanofibrils, nanocrystals, and bacterial nanocellulose into cell‐instructive scaffolds for skin, bone ...
Aurora Rodríguez Martínez +6 more
wiley +1 more source
Transcription factors OCT4, SOX2, KLF4, C‐MYC, and NANOG (OSKM‐N) regulate pluripotency and stemness, and their ectopic expression reprograms human and murine fibroblasts that constitute the key of regenerative medicine. To determine their contribution to cell transformation, we analyzed the gene expression profiles of these transcription factors in ...
Graciela Ruiz +10 more
wiley +1 more source
Los géneros Cestrum, Sessea y Vestia pertenecen a la tribu Cestreae y presentan varias características cromosómicas que los diferencian de otras especies de Solanaceae, como el número y tamaño cromosómico.
Aquiles Frossasco +2 more
doaj +1 more source
Autoimmune diseases are chronic conditions that result from an inadequate immune response to self-antigens and affect many people worldwide. Their signs, symptoms, and clinical severity change throughout the course of the disease, therefore the diagnosis
Karen Álvarez, Mauricio Rojas
doaj +1 more source
Cervical cancer is the second most frequent tumor type in women worldwide with cases developing clinical recurrence, metastasis, and chemoresistance. The cancer stem cells (CSC) may be implicated in tumor resistance to therapy. RESveratrol (RES), a natural compound, is an antioxidant with multiple beneficial activities.
Graciela Ruíz +6 more
wiley +1 more source

