Results 101 to 110 of about 490,642 (236)

Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy

Scientific Reports, 2012
To investigate whether altered energy metabolism induces the Warburg effect and results in tumor malignancy, the respiratory enzyme citrate synthase (CS) was examined, silenced and the effects analyzed. In human cervical carcinoma cells, RNAi-mediated CS
Chin-Chih Lin, T. Cheng, W. Tsai, Hui-Ju Tsai, Keng-Hsun Hu, Hao-Chun Chang, C. Yeh, Ying-Chou Chen, Ching-Chun Liao, Wen-Tsan Chang   +9 more
semanticscholar   +1 more source

Regulation of Expression of Citrate Synthase by the Retinoic Acid Receptor-Related Orphan Receptor α (RORα)

PLoS ONE, 2012
The retinoic acid receptor-related orphan receptor α (RORα) is a member of the nuclear receptor superfamily of transcription factors that plays an important role in regulation of the circadian rhythm and metabolism. Mice lacking a functional RORα display
Christine Crumbley, Yongjun Wang, Subhashish Banerjee, T. Burris   +3 more
semanticscholar   +1 more source

Adaptations in Mitochondrial Enzymatic Activity Occurs Independent of Genomic Dosage in Response to Aerobic Exercise Training and Deconditioning in Human Skeletal Muscle

Cells, 2019
Mitochondrial DNA (mtDNA) replication is thought to be an integral part of exercise-training-induced mitochondrial adaptations. Thus, mtDNA level is often used as an index of mitochondrial adaptations in training studies.
Andreas M. Fritzen, Frank B. Thøgersen, Kasper Thybo, Christoffer R. Vissing, Thomas O. Krag, Cristina Ruiz-Ruiz, Lotte Risom, Flemming Wibrand, Louise D. Høeg, Bente Kiens, Morten Duno, John Vissing, Tina D. Jeppesen   +12 more
doaj   +1 more source

Novel Rickettsia in Ticks, Tasmania, Australia

Emerging Infectious Diseases, 2009
A novel rickettsia was detected in Ixodes tasmani ticks collected from Tasmanian devils. A total of 55% were positive for the citrate synthase gene by quantitative PCR.
Leonard Izzard, Stephen Graves, Erika Cox, Stan Fenwick, Nathan Unsworth, John Stenos   +5 more
doaj   +1 more source

Head to head comparison of short-term treatment with the NAD+ precursor nicotinamide mononucleotide (NMN) and six weeks of exercise in obese female mice

Frontiers in Pharmacology, 2016
Obesity is well known to be a major cause of several chronic metabolic diseases, which can be partially counteracted by exercise. This is due, in part, to an upregulation of mitochondrial activity through increased nicotinamide adenine dinucleotide (NAD+)
Golam Mezbah Uddin, Neil A Youngson, David A Sinclair, David A Sinclair, Margaret J Morris   +4 more
doaj   +1 more source

T-DNA promoter tagging in Nicotiana tabacum : a thesis presented in fulfilment of the requirements for the degree of Master of Philosophy in Genetics at Massey University, Palmerston North, New Zealand [PDF]

, 1997
Plant development is primarily controlled at the level of gene expression. In order to analyse this regulation it is necessary to isolate genes which are involved in organ development through cellular and tissue determination or which respond to ...
Kerr, Donald Haldane
core  

Viral hijacking of cellular metabolism. [PDF]

, 2019
This review discusses the current state of the viral metabolism field and gaps in knowledge that will be important for future studies to investigate.
Ch'ng, James, Christofk, Heather R, Thaker, Shivani K   +2 more
core  

Characterization of water and wildlife strains as a subgroup of Campylobacter jejuni using DNA microarrays.

, 2013
Campylobacter jejuni is the leading cause of human bacterial gastroenteritis worldwide, but source attribution of the organism is difficult. Previously, DNA microarrays were used to investigate isolate source, which suggested a non-livestock source of ...
Altschul, Brandl, Champion, Dingle, Dingle, Dorrell, Ethelberg, Francisco, French, Gundogdu, Harris, Hepworth, Hepworth, Hinchliffe, Howard, Huelsenbeck, Jensen, Jorgensen, Joshua, Kalendar, Karenlampi, Katoh, Katoh, Kemp, Kim, Kim, King, Kwan, Kwan, Manning, McCarthy, Mellmann, Miller, Moen, Murphy, Ogden, On, Park, Pearson, Petersen, Ronquist, Rosef, Rosef, Sails, Sanad, Schonberg-Norio, Skirrow, Skirrow, Stabler, Staden, Staden, Taboada, Taboada, Tam, Tam, Wilson   +55 more
core   +1 more source

Citrate Synthase Overexpression of Pseudomonas putida Increases Succinate Production from Acetate in Microaerobic Cultivation. [PDF]

ACS Omega, 2023
Mutyala S, Li S, Khandelwal H, Kong DS, Kim JR.   +4 more
europepmc   +1 more source

Metabolic features of neutrophilic differentiation of HL-60 cells in hyperglycemic environments

BMJ Open Diabetes Research & Care
Introduction Chronic hyperglycemia affects neutrophil functions, leading to reduced pathogen killing and increased morbidity. This impairment has been directly linked to increased glycemia, however, how this specifically affects neutrophils metabolism ...
Gerardo Garcia-Rivas, Jorge Andrés Cázares-Preciado, Alejandra López-Arredondo, José Antonio Cruz-Cardenas, Luis Alberto Luévano-Martínez, Heriberto Prado-Garcia, Marion E. G. Brunck   +6 more
doaj   +1 more source