Results 101 to 110 of about 142,996 (390)

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Determining the effect of cadmium on embryogenesis in isolated administration and in combination with selenium and germanium citrates.

Medičnì Perspektivi, 2020
Cadmium compounds found in biological systems form the ecological crisis of the planet. An urgent task for researchers is to determine the morphological changes that occur in the body under the action of cadmium compounds in both prenatal and postnatal ...
O. O. Nefyodov, D. V. Bilyshko, K. A. Kushnaryova, O. S. Shevchenko, V. F. Shatorna, O. I. Kefeli-Ianovska, O. G. Kozlovskaya   +6 more
doaj   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Infectious urolithiasis

Pediatria i Medycyna Rodzinna, 2019
Infectious urolithiasis is a form of urolithiasis associated with the presence of bacteria in the urinary tract (Proteus spp., Klebsiella spp., Providencia spp., Pseudomonas, Morganella morganii and Staphylococcus aureus).
Piotr Skrzypczyk, Małgorzata Pańczyk-Tomaszewska   +1 more
doaj   +1 more source

Internal preference mapping of milk–fruit beverages: Influence of color and appearance on its acceptability [PDF]

, 2018
The individual preferences of 100 consumers between 20 and 30 years old for the color of 16 milk–fruit juice beverages (MFJB) were investigated by preference mapping technique.
Chaya, Carolina, Fernández Vázquez, Rocío, Heredia Mira, Francisco José, Hernanz Vila, María Dolores, Stinco Scanarotti, Carla Maria, Vicario Romero, Isabel   +5 more
core   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

FEATURES OF BIOELEMENTS ACCUMULATION BY FUNGI L. EDODES DURING CULTIVATION IN SUBSTRATES ENRICHED WITH Cr, Se, Ge, Fe CITRATES

Harčova Nauka ì Tehnologìâ
The paper investigates the features of citrates Cr, Se, Ge, Fe biotransformation during the cultivation of Lentinula Edodes and their influence on the accumulation of some bioelements in order to predict the biological value, therapeutic and prophylactic
I. Andrusyshyna, O. Velikanov, D. Bakhlukov   +2 more
doaj   +1 more source

Investigation of antimicrobial activity of silver and copper citrate for the development of pharmaceuticals preparations

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
The fast formation of microbial resistance to antibiotics creates necessity of search for new alternative antimicrobial drugs. Aim. To study the specific antimicrobial activity of silver citrate and copper citrate for the purpose of pharmaceutical ...
Z. N. Polova
doaj   +1 more source

Synthesis, structural characterization and broadband ferromagnetic resonance in Li ferrite nanoparticles [PDF]

, 2018
Producción CientíficaLithium ferrites are well known materials due to its numerous technological applications especially in microwave devices. Lithium ferrite nanoparticles were prepared by sol-gel technique by means of Pechini method, and then annealed ...
Almeida Valente, Manuel, Fernandes Graça, Manuel Pedro, Hernández Gómez, Pablo, Muñoz Muñoz, José María   +3 more
core   +1 more source