Results 121 to 130 of about 124,247 (335)

Evaluation of fouling and chemical cleaning of reverse osmosis membrane after treatment of geothermal water

open access: yesFrontiers in Membrane Science and Technology
In this study, high mineral scaling propensity geothermal water was treated using a FilmTech BW30-2540 reverse osmosis (RO) membrane, integrated into a mini-pilot scale membrane test unit installed at a geothermal heating center.
Aseel Zaid   +8 more
doaj   +1 more source

Construction of PANoptosis‐Inhibiting Carbonized Polymer Dots via Machine Learning Potential for Mitigating Chemodrug‐Induced Nephrotoxicity

open access: yesAdvanced Science, EarlyView.
An enhanced sampling method is developed for molecular dynamics based on trained machine learning force fields to guide the construction of PANoptosis‐inhibiting carbonized polymer dots (Lu‐CDs) derived from a flavonoid compound for treating chemodrug‐induced nephrotoxicity.
Xinchen Liu   +8 more
wiley   +1 more source

Integrating glycolysis, citric acid cycle, pentose phosphate pathway, and fatty acid beta-oxidation into a single computational model. [PDF]

open access: yesSci Rep, 2023
Kloska SM   +6 more
europepmc   +1 more source

Temporal and Spatial Impact of Human Cadaver Decomposition on Soil Bacterial and Arthropod Community Structure and Function [PDF]

open access: yes, 2018
As vertebrate carrion decomposes, there is a release of nutrient-rich fluids into theunderlying soil, which can impact associated biological community structure andfunction. How these changes alter soil biogeochemical cycles is relatively unknown and may
Benbow, M. Eric   +9 more
core   +1 more source

CD27 and ICOS as Targets of PD‐1/PD‐L1 Signaling to Regulate Resident Memory CD8+ T‐Cell‐Mediated Pulmonary Protection and Pathology

open access: yesAdvanced Science, EarlyView.
Here it is revealed that the costimulatory receptors CD27 and ICOS are essential for the long‐term maintenance of PD‐1high CD8+ TRM cells following influenza infection. PD‐L1 blockade enhances the proliferation and activation of these cells through Nur77 activation downstream of the CD27/ICOS signaling axis, thereby boosting host immunity against ...
Yuanyuan Chen   +16 more
wiley   +1 more source

Metabolomics analysis of cerebrospinal fluid suggests citric acid cycle aberrations in bipolar disorder. [PDF]

open access: yesNeurosci Appl, 2022
Smedler E   +6 more
europepmc   +1 more source

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao   +18 more
wiley   +1 more source

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