Results 51 to 60 of about 3,771 (212)

Genetic ancestry–concordant ceramide metabolism and response to androgen receptor pathway inhibition in metastatic castration‐resistant prostate cancer

Cancer, Volume 132, Issue 11, 1 June 2026.
Abstract Background The authors observed differences in response between Black and White patients with metastatic castration‐resistant prostate cancer (mCRPC) who were treated prospectively with androgen receptor pathway inhibition (ARPI) in the Abi Race and PANTHER studies.
Sean A. Piwarski, Lauren E. Howard, Morgan A. Paul, Nick Bachelder, Bonnie LaCroix, Angela Clayton, Donna Allen, Julie Kephart, Andrew J. Armstrong, Steven R. Patierno, Daniel J. George, Terry Hyslop, Jennifer A. Freedman   +12 more
wiley   +1 more source

Effect of low expression level of acetyl coenzyme A synthetase gene on secondary metabolite in Monascus

Czech Journal of Food Sciences, 2022
Acetyl-coenzyme A (CoA) is a key metabolite produced by the acetyl-CoA synthetase (ACS) gene in energy metabolism and biosynthetic pathways. ACS is speculated to be the branching site of monacolin K (MK) and citrinin production and related to the ...
Lin Lin, Chundan Zhang, Xinman Shao, Pupin Liu, Zhangfei Wu, Yanxia Lu, Hongzhen Guo   +6 more
doaj   +1 more source

Enteric Nervous System Damage by Food Contaminants: A Pathway to Neurodegeneration?

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT The enteric nervous system (ENS), a key component of the gut–brain axis, has emerged as a critical player in the pathogenesis of Parkinson's disease (PD). It is the first neural system exposed to food contaminants (FCs)—a diverse group of ubiquitous toxic compounds fortuitously present in food derived from production, processing, storage, or ...
Helena Ramos, Ana Margarida Araújo, Isabel M. P. L. V. O. Ferreira, Miguel A. Faria   +3 more
wiley   +1 more source

Compounds and antibodies for the immunodetection of citrinin

, 2023
[EN] Compounds and antibodies for the immunodetection of citrinin. The present invention relates to compounds, especially conjugates and derivatives of citrinin labeled by a novel position of the molecule, suitable for the production of high-affinity ...
Agulló, Consuelo, Abad Fuentes, Antonio, Abad Somovilla, Antonio, Mercader Badia, Josep Vicent, Navarro Fuertes, Ismael, Ulloa Campos, Diego Alonso   +5 more
core  

Safety evaluation of the food enzyme containing metalloendopeptidase and leucyl aminopeptidase activities from the non‐genetically modified Aspergillus oryzae strain HBI‐POP01

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract The food enzyme containing metalloendopeptidase (EC 3.4.24) and leucyl aminopeptidase (EC 3.4.11.1) activities is produced with the non‐genetically modified Aspergillus oryzae strain HBI‐POP01 by HBI Enzymes Inc. The food enzyme was considered free from viable cells of the production organism.
EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Henk Van Loveren, Laurence Vernis, Ana Criado, Jaime Aguilera, Magdalena Andryszkiewicz, Daniele Cavanna, Cristina Fernández‐Fraguas, Giulio di Piazza, Yi Liu   +19 more
wiley   +1 more source

Biosynthesis of citrinin and synthesis of its biogenetic precursors

, 1981
The biosynthetic pathway to citrinin has been elucidated by incorporation studies with advanced precursors. These specifically labelled compounds were obtained from labelled citrinin produced by cultures of Penicillium citrinum in the presence of [Me-14C]
C. Scolastico, F. Aragozzini, C.M.A. Gennari, C. Merendi, L. Colombo, D. Potenza   +5 more
core   +1 more source

Functional analysis of Monascus ruber M7 and MrVeA gene related mutants by light control [PDF]

Zhongguo niangzao
In order to investigate the effect of light control on the function of Monascus ruber M7 and MrVeA gene related mutant ΔMrVeA, OEMrVeA, the gene deletion strain (ΔMrVeA) and overexpression strain (OEMrVeA) were constructed by MrVeA gene knockout and ...
ZHAO Yuxia, HE Xia, WANG Liling, HUANG Huihui, KUANG Linsha, HE Yi
doaj   +1 more source

Citrinin in Foods and Supplements: A Review of Occurrence and Analytical Methodologies

Foods, 2020
Citrinin (CIT) deserves attention due to its known toxic effects in mammalian species and its widespread occurrence in food commodities, often along with ochratoxin A, another nephrotoxic mycotoxin. Human exposure, a key element in assessing risk related
Liliana J. G. Silva, André M. P. T. Pereira, Angelina Pena, Celeste M. Lino   +3 more
doaj   +1 more source

Ochratoxin A and Citrinin Differentially Modulate Bovine Mammary Epithelial Cell Permeability and Innate Immune Function

Toxins, 2022
Frequent detection of mycotoxins ochratoxin A (OTA) and citrinin (CIT) in ruminant feed and feedstuff can be a potential threat to feed safety, animal performance and health.
Ran Xu, Umesh K. Shandilya, Alexandros Yiannikouris, Niel A. Karrow   +3 more
doaj   +1 more source

Safety and efficacy of a feed additive consisting of l‐valine produced with Corynebacterium glutamicum CCTCC M 20232578 for all animal species (Kempex Holland B.V.)

EFSA Journal, Volume 24, Issue 5, May 2026.
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l‐valine produced with a non‐genetically modified strain of Corynebacterium glutamicum (CCTCC M 20232578) as a nutritional feed additive, to be used in feed or water for drinking for all animal species and categories ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Giovanna Martelli, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Katerina Theodoridou, Montserrat Anguita, Nicole Bozzi Cionci, Matteo Innocenti, Maria Kolona, Elisa Pettenati, Jordi Tarrés‐Call   +22 more
wiley   +1 more source