Citrinin inhibits the function of Leydig cells in male rats in prepuberty
Ecotoxicology and Environmental Safety, 2023 Citrinin, a mycotoxin existing in fruits, has nephrotoxicity, hepatotoxicity and embryotoxicity. The effects of citrinin on Leydig cell development in prepuberty remains unclear.
Ren-Shan Ge, Yiyan Wang, Jianmin Sang
exaly +3 more sources
Chromosome-Scale Genome Analysis Reveals Locus-Specific Disruption of the Citrinin-Associated Region in a Furu-Derived <i>Monascus ruber</i> Strain BC20. [PDF]
FoodsMonascus species are widely used in traditional fermented foods for pigment and flavor formation, but citrinin contamination remains a major safety concern that limits broader food applications.
Zhang H +8 more
europepmc +2 more sources
Four New Citrinin Derivatives from a Marine-Derived Penicillium sp. Fungal Strain
Molecules, 2013 Four new citrinin derivatives, including two citrinin dimers and two citrinin monomer derivatives, were isolated and identified from a marine-derived fungal strain Penicillium sp. ML226 along with six known related compounds.
Zhong Zheng, Zhi Hu
exaly +3 more sources
Derivation of Human Toxicokinetic Parameters and Chemical-Specific Adjustment Factor of Citrinin Through a Human Intervention Trial and Hierarchical Bayesian Population Modeling. [PDF]
Toxins (Basel)Background: Citrinin (CIT) is a mycotoxin produced by various fungi contaminating stored cereals and fruits. While biomonitoring and food occurrence data indicate widespread exposure, its public health risks remain unclear due to the lack of human ...
Visintin L +5 more
europepmc +2 more sources
Evaluating the combined toxicity of Penicillium mycotoxins in absorption, metabolism, and excretion systems. [PDF]
J Sci Food AgricAbstract BACKGROUND Penicillium mycotoxins, including ochratoxin A (OTA), citrinin (CIT), and cyclopiazonic acid (CPZ), frequently co‐occur in food commodities, contributing to chronic low‐level dietary exposure. However, current risk assessments often consider these toxins individually, overlooking potential interaction effects.
Monteiro CS +3 more
europepmc +2 more sources
The role of ER stress and ATP/AMPK in oxidative stress meditated hepatotoxicity induced by citrinin
Ecotoxicology and Environmental Safety, 2022 Citrinin, a secondary metabolite, can pose serious risks to the environment and organisms, but its hepatotoxic mechanisms are still unclear. Histopathological and ultrastructural results showed that citrinin-induced liver injury in Kunming mice, and the ...
Jing Wu +12 more
doaj +1 more source
Toxins, 2021 Historically, the analysis of citrinin has mainly been performed on cereals such as red yeast rice; however, in recent years, more complex and abnormal commodities such as spices and infant foods are becoming more widely assessed.
Christopher Mair +7 more
doaj +1 more source
Life, 2023 The mycotoxin citrinin, which can contaminate food, is a major global concern. Citrinin is regarded as an inevitable pollutant in foods and feed since fungi are widely present in the environment.
Seema Zargar, Tanveer A. Wani
doaj +1 more source
Guiding Molecularly Imprinted Polymer Design by Pharmacophore Modeling
Molecules, 2021 Molecularly imprinted polymers (MIP) combine the selectivity of immunoaffinity chromatography with the robustness of common solid-phase extraction in what is referred to as molecularly imprinted solid-phase extraction (MISPE). This contribution shows how
Wiebke Derz +2 more
doaj +1 more source
AMB Express, 2020 Monascus can produce many beneficial metabolites; however, it can simultaneously also produce citrinin, which seriously limits its application. Therefore, reducing the production of citrinin is of great interest. Herein, Monascus aurantiacus Li AS3.4384 (
Yanling Wang +4 more
doaj +1 more source