Secondary Metabolites with Antifungal Activities from Mangrove Derived Fungus Monascus purpureus WMD2424 [PDF]
Marine Drugs, 2023 The mold Monascus, also called red yeast rice, anka, or koji, has been used as the natural food coloring agent and food additives for more than 1000 years in Asian countries. It has also been used in Chinese herbology and traditional Chinese medicine due
Ming-Der Wu +2 more
doaj +3 more sources
The pharmacology and mechanism of action of Monascus purpureus Went: a scoping review [PDF]
Frontiers in PharmacologyObjectiveThe aim of this study is to review the recent studies on the pharmacology and mechanism of action of Monascus purpureus Went, analyze its medicinal value, and explore future research directions.MethodA scoping review was conducted by searching ...
Sitong Liu +11 more
doaj +4 more sources
Methionine and S-Adenosylmethionine Regulate Monascus Pigments Biosynthesis in Monascus purpureus [PDF]
Frontiers in Microbiology, 2022 Amino acid metabolism could exert regulatory effects on Monascus pigments (MPs) biosynthesis. In this work, MPs biosynthesis regulated by methionine and S-adenosylmethionine (SAM) was investigated in Monascus purpureus RP2. The results indicated that the
Sheng Yin +5 more
doaj +4 more sources
Investigation of Citrinin and Pigment Biosynthesis Mechanisms in Monascus purpureus by Transcriptomic Analysis [PDF]
Frontiers in Microbiology, 2018 Monascus purpureus YY-1 is widely used in food colorant production in China. Our previous study clearly illustrated the whole-genome data for YY-1 and provided useful insight into evolutionary research and industrial applications.
Bin Liang, Xin-Jun Du, Wenbo Wang
exaly +4 more sources
Assimilation of Cholesterol by Monascus purpureus. [PDF]
J Fungi (Basel), 2020 Monascus purpureus, a filamentous fungus known for its fermentation of red yeast rice, produces the metabolite monacolin K used in statin drugs to inhibit cholesterol biosynthesis. In this study, we show that active cultures of M. purpureus CBS 109.07, independent of secondary metabolites, use the mechanism of cholesterol assimilation to lower ...
Nguyen TPT +4 more
europepmc +6 more sources
Enhanced Monacolin K Production in Monascus purpureus Via Mutagenesis and Nitrogen Source Optimization. [PDF]
J Basic MicrobiolABSTRACT Monascus fungi are valued for their production of Monacolin K (MK), a bioactive compound with recognized lipid‐lowering and multifunctional properties. To enhance MK yield in solid‐state fermentation, this study combined atmospheric and room‐temperature plasma (ARTP) mutagenesis with L‐arginine supplementation.
Yang C, Yajing Y, Housheng H.
europepmc +2 more sources
Analysis of secondary metabolite gene clusters and chitin biosynthesis pathways of Monascus purpureus with high production of pigment and citrinin based on whole-genome sequencing. [PDF]
PLoS ONE, 2022 Monascus is a filamentous fungus that is widely used for producing Monascus pigments in the food industry in Southeast Asia. While the development of bioinformatics has helped elucidate the molecular mechanism underlying metabolic engineering of ...
Song Zhang +3 more
doaj +3 more sources
Co-Culture of Monascus purpureus and Aspergillus niger Isolated from Wuyi Hongqu to Enhance Monascus Pigments Production While Inhibiting Citrinin Production [PDF]
Journal of FungiWuyi Hongqu (WYH), also called black-skin-red-koji, which has been utilizing as a fermentation starter for more than one thousand years in China, is a symbiotic combination of Monascus spp.
Qin Yu, Xi Yuan, Fusheng Chen
doaj +2 more sources
RNA-Seq Insight into the Impact and Mechanisms of Methyl Donor and Glycine Betaine Osmoprotectant on Polyketide Secondary Metabolism in Monascus purpureus M1 [PDF]
Journal of FungiGlycine betaine (GB) serves as both a methyl donor and osmoprotectant in microorganisms, facilitating growth and enhancing metabolic product yields. While the polyketide metabolites from Monascus purpureus, such as Monascus pigments (MPs) and monacolin K
Zheng Liu +7 more
doaj +2 more sources
Disruption of the Chitin Biosynthetic Pathway Results in Significant Changes in the Cell Growth Phenotypes and Biosynthesis of Secondary Metabolites of Monascus purpureus [PDF]
Journal of Fungi, 2022 In this study, the gene monascus-5162 from Monascus purpureus LQ-6, identified as chitin synthase gene VI (chs6), was knocked out to disrupt the chitin biosynthetic pathway and regulate the biosynthesis of Monascus pigments (MPs) and citrinin.
Meng Shu +8 more
doaj +2 more sources