The pharmacology and mechanism of action of Monascus purpureus Went: a scoping review [PDF]
Frontiers in PharmacologyObjectiveThe aim of this study is to review the recent studies on the pharmacology and mechanism of action of Monascus purpureus Went, analyze its medicinal value, and explore future research directions.MethodA scoping review was conducted by searching ...
Myeong Soo Lee, Lin Ang, Junhua Zhang
exaly +4 more sources
Secondary Metabolites with Antifungal Activities from Mangrove Derived Fungus Monascus purpureus WMD2424 [PDF]
Marine Drugs, 2023 The mold Monascus, also called red yeast rice, anka, or koji, has been used as the natural food coloring agent and food additives for more than 1000 years in Asian countries. It has also been used in Chinese herbology and traditional Chinese medicine due
Ming-Der Wu +2 more
doaj +2 more sources
Enhanced Monacolin K Production in Monascus purpureus Via Mutagenesis and Nitrogen Source Optimization. [PDF]
J Basic MicrobiolABSTRACT Monascus fungi are valued for their production of Monacolin K (MK), a bioactive compound with recognized lipid‐lowering and multifunctional properties. To enhance MK yield in solid‐state fermentation, this study combined atmospheric and room‐temperature plasma (ARTP) mutagenesis with L‐arginine supplementation.
Yang C, Yajing Y, Housheng H.
europepmc +2 more sources
Analysis of secondary metabolite gene clusters and chitin biosynthesis pathways of Monascus purpureus with high production of pigment and citrinin based on whole-genome sequencing. [PDF]
PLoS ONE, 2022 Monascus is a filamentous fungus that is widely used for producing Monascus pigments in the food industry in Southeast Asia. While the development of bioinformatics has helped elucidate the molecular mechanism underlying metabolic engineering of ...
Song Zhang +3 more
doaj +3 more sources
Co-Culture of Monascus purpureus and Aspergillus niger Isolated from Wuyi Hongqu to Enhance Monascus Pigments Production While Inhibiting Citrinin Production [PDF]
Journal of FungiWuyi Hongqu (WYH), also called black-skin-red-koji, which has been utilizing as a fermentation starter for more than one thousand years in China, is a symbiotic combination of Monascus spp.
Qin Yu, Xi Yuan, Fusheng Chen
doaj +2 more sources
RNA-Seq Insight into the Impact and Mechanisms of Methyl Donor and Glycine Betaine Osmoprotectant on Polyketide Secondary Metabolism in Monascus purpureus M1 [PDF]
Journal of FungiGlycine betaine (GB) serves as both a methyl donor and osmoprotectant in microorganisms, facilitating growth and enhancing metabolic product yields. While the polyketide metabolites from Monascus purpureus, such as Monascus pigments (MPs) and monacolin K
Zheng Liu +7 more
doaj +2 more sources
Disruption of the Chitin Biosynthetic Pathway Results in Significant Changes in the Cell Growth Phenotypes and Biosynthesis of Secondary Metabolites of Monascus purpureus [PDF]
Journal of Fungi, 2022 In this study, the gene monascus-5162 from Monascus purpureus LQ-6, identified as chitin synthase gene VI (chs6), was knocked out to disrupt the chitin biosynthetic pathway and regulate the biosynthesis of Monascus pigments (MPs) and citrinin.
Meng Shu +8 more
doaj +2 more sources
Co-culture with Lactobacillus plantarum SC-1 facilitates ergosterol synthesis in Monascus purpureus through MpSet1-affected H3K4ac establishment [PDF]
Frontiers in MicrobiologyIntroductionIn fungi, ergosterol synthesis is regulated by multiple transcription factors such as Upc2, but the regulation of ergosterol synthesis in Monascus remains unclear.MethodsWe performed a co-culture system of Monascus purpureus (M.
Zhongling Wu, Zhenmin Liu
doaj +2 more sources
Isolation of Monascus purpureus HC-5 and Optimization of Solid-State Fermentation for High-Yield Pigment Production [PDF]
MicroorganismsMonascus pigments (MPs) are valuable natural colorants, but their industrial production is often hampered by scarce high-yield strains and inefficient processes.
Wenli Quan +5 more
doaj +2 more sources
Investigations into Chemical Components from Monascus purpureus with Photoprotective and Anti-Melanogenic Activities [PDF]
Journal of Fungi, 2021 Monascus species are asexually or sexually reproduced homothallic fungi that can produce a red colorant, specifically the so-called red yeast rice or Anka, which is used as a food ingredient in Asia. Traditional experiences of using Monascus for treating
Ho-Cheng Wu +5 more
doaj +2 more sources