Results 31 to 40 of about 9,594 (241)

Post-mortem magnetic resonance imaging in patients with suspected prion disease: Pathological confirmation, sensitivity, specificity and observer reliability. A national registry.

PLoS ONE, 2018
The relationship between magnetic resonance imaging (MRI) and clinical variables in patients suspected to have Creutzfeldt-Jakob Disease (CJD) is uncertain.
Lorna M Gibson, Francesca M Chappell, David Summers, Donald A Collie, Robin Sellar, Jonathan Best, Richard Knight, James W Ironside, Joanna M Wardlaw   +8 more
doaj   +1 more source

Creutzfeldt-Jakob Disease in a Tertiary Care Hospital in Thailand: A Case Series and Review of the Literature [PDF]

Journal of Movement Disorders, 2015
Creutzfeldt-Jakob Disease (CJD) is an incurable and inevitably fatal neurodegenerative disorder. Although CJD has a worldwide distribution, there are no official statistics on CJD in Thailand.
Praween Lolekha, Ahmed Rasheed, Chutanat Yotsarawat   +2 more
doaj   +1 more source

Surveillance for Creutzfeldt-Jakob disease in China from 2006 to 2007

BMC Public Health, 2008
Background Human transmissible spongiform encephalopathies (HTSE), or Creutzfeldt-Jakob disease (CJD), is a group of rare and fatal diseases in central nervous system.
Wang Xiao-Fang, Xiang Ni-Juan, Han Jun, Jiang Hui-Ying, Tian Chan, Chen Jian-Ming, Zhang Bao-Yun, Zhou Wei, Gao Chen, Shi Qi, Gao Yong-Jun, Dong Xiao-Ping   +11 more
doaj   +1 more source

Human prion diseases in the United States. [PDF]

PLoS ONE, 2010
BackgroundPrion diseases are a family of rare, progressive, neurodegenerative disorders that affect humans and animals. The most common form of human prion disease, Creutzfeldt-Jakob disease (CJD), occurs worldwide. Variant CJD (vCJD), a recently emerged
Robert C Holman, Ermias D Belay, Krista Y Christensen, Ryan A Maddox, Arialdi M Minino, Arianne M Folkema, Dana L Haberling, Teresa A Hammett, Kenneth D Kochanek, James J Sejvar, Lawrence B Schonberger   +10 more
doaj   +1 more source

3‐Deoxy‐3‐Fluoro Mannuronic Acid Alginates: Stereoselective Automated Synthesis and Conformational Behaviour

Angewandte Chemie, EarlyView.
The impact of C‐3 fluorination on the synthesis and conformation of alginate oligosaccharides is investigated. A C‐3‐fluoro mannuronic acid building block is generated and shown to react with high β‐selectivity. Automated glycan assembly enables access to uniquely fluorinated mannuronic acid alginates where deoxyfluorination is shown not to perturb the
Sean T. Evans, Nishu Yadav, Wouter A. Remmerswaal, Daan Hoogers, Koen N. A. van de Vrande, Sarah Hosking, Ana Poveda, Jeroen D. C. Codée, Jesús Jiménez‐Barbero, Martina Delbianco, Gavin J. Miller   +10 more
wiley   +2 more sources

Creutzfeldt-Jakob Disease in the United States, 1979-1994: Using National Mortality Data to Assess the Possible Occurrence of Variant Cases

Emerging Infectious Diseases, 1996
After a cluster of Creutzfeldt-Jakob disease (CJD) cases among unusually young patients was reported recently from the United Kingdom, we examined trends and the current incidence of CJD in the United States. We found that the age-adjusted CJD death rate
Robert C. Holman, Ali S. Khan, Ermias D. Belay, Lawrence B. Schonberger   +3 more
doaj   +1 more source

Rapid and Sensitive RT-QuIC Detection of Human Creutzfeldt-Jakob Disease Using Cerebrospinal Fluid

mBio, 2015
Fast, definitive diagnosis of Creutzfeldt-Jakob disease (CJD) is important in assessing patient care options and transmission risks. Real-time quaking-induced conversion (RT-QuIC) assays of cerebrospinal fluid (CSF) and nasal-brushing specimens are ...
Christina D. Orrú, Bradley R. Groveman, Andrew G. Hughson, Gianluigi Zanusso, Michael B. Coulthart, Byron Caughey   +5 more
doaj   +1 more source

The prepared tau exon-specific antibodies revealed distinct profiles of tau in CSF of the patients with Creutzfeldt-Jakob disease. [PDF]

PLoS ONE, 2010
BACKGROUND: The diagnostic value of CSF tau for Creutzfeldt-Jakob disease (CJD) has been widely evaluated, showing a markedly disease-relative manner. However, the profiles of tau isoforms in CSF of CJD patients remain unknown. Here, we prepared the exon-
Cao Chen, Qi Shi, Bao-Yun Zhang, Gui-Rong Wang, Wei Zhou, Chen Gao, Chan Tian, Guo-Yong Mei, Yan-Ling Han, Jun Han, Xiao-Ping Dong   +10 more
doaj   +1 more source

Creutzfeldt-Jakob disease: recent developments [version 1; referees: 2 approved]

F1000Research, 2017
Creutzfeldt-Jakob disease (CJD) is a rare prion disorder that has been the subject of both professional and public interest following the identification of variant CJD as a zoonotic disorder.
Graeme Mackenzie, Robert Will
doaj   +1 more source

A nationwide trend analysis in the incidence and mortality of Creutzfeldt–Jakob disease in Japan between 2005 and 2014

Scientific Reports, 2020
In the era of hyper-ageing, Creutzfeldt–Jakob disease (CJD) can become more prevalent as an important cause of dementia. This study aimed to evaluate the trends in crude and age-adjusted CJD-associated mortality and incidence rates in Japan using ...
Yoshito Nishimura, Ko Harada, Toshihiro Koyama, Hideharu Hagiya, Fumio Otsuka   +4 more
doaj   +1 more source