Results 21 to 30 of about 9,594 (241)

A clinicopathological study of selected cognitive impairment cases in Lothian, Scotland: enhanced CJD surveillance in the 65 + population group

BMC Geriatrics, 2022
Background Variant Creutzfeldt-Jakob Disease (vCJD) is primarily associated with dietary exposure to bovine-spongiform-encephalopathy. Cases may be missed in the elderly population where dementia is common with less frequent referral to specialist ...
Lovney Kanguru, Gemma Logan, Briony Waddel, Colin Smith, Anna Molesworth, Richard Knight   +5 more
doaj   +1 more source

CJD mimics and chameleons [PDF]

Practical Neurology, 2017
Rapidly progressive dementia mimicking Creutzfeldt–Jakob disease (CJD) is a relatively rare presentation but a rewarding one to become familiar with, as the potential diagnoses range from the universally fatal to the completely reversible. Patients require urgent decisions about assessment and investigation and have quickly evolving needs for ...
Mead, S, Rudge, P
openaire   +3 more sources

Plasma Lipocalin 2 in Alzheimer’s disease: potential utility in the differential diagnosis and relationship with other biomarkers

Alzheimer’s Research & Therapy, 2022
Background Lipocalin-2 is a glycoprotein that is involved in various physiological and pathophysiological processes. In the brain, it is expressed in response to vascular and other brain injury, as well as in Alzheimer’s disease in reactive microglia and
Peter Hermann, Anna Villar-Piqué, Matthias Schmitz, Christian Schmidt, Daniela Varges, Stefan Goebel, Timothy Bunck, Hanna Lindemann, Carla Bogner, Isabel Santana, Inês Baldeiras, Joachim Riggert, Inga Zerr, Franc Llorens   +13 more
doaj   +1 more source

Plasma YKL-40 in the spectrum of neurodegenerative dementia

Journal of Neuroinflammation, 2019
Background Increased plasma YKL-40 has been reported in Alzheimer’s disease (AD), but its levels in other neurodegenerative diseases are unknown. Here, we aimed to investigate plasma YKL-40 in the spectrum of neurodegenerative dementias.
Anna Villar-Piqué, Matthias Schmitz, Peter Hermann, Stefan Goebel, Timothy Bunck, Daniela Varges, Isidre Ferrer, Joachim Riggert, Franc Llorens, Inga Zerr   +9 more
doaj   +1 more source

Case report: Two clusters of Creutzfeldt–Jakob disease cases within 1 year in West Michigan

Frontiers in Neurology, 2023
BackgroundCreutzfeldt–Jakob disease (CJD) is a rare, rapidly progressive, and uniformly fatal neurodegenerative disease. The reported incidence of CJD is 1 to 2 per million people worldwide annually, with fewer than 1,000 cases in the United States per ...
Ling Ling Rong, Nicholas J. Lannen, Evan C. Tank, Jessica L. Feistel, Christopher J. Therasse, Anvita Potluri, Muhib Khan, Jiangyong Min   +7 more
doaj   +1 more source

Study protocol for enhanced CJD surveillance in the 65+ years population group in Scotland: an observational neuropathological screening study of banked brain tissue donations for evidence of prion disease

BMJ Open, 2019
Introduction Creutzfeldt-Jakob disease (CJD) is a human prion disease that occurs in sporadic, genetic and acquired forms. Variant CJD (vCJD) is an acquired form first identified in 1996 in the UK. To date, 178 cases of vCJD have been reported in the UK,
Colin Smith, Alexander Howard Peden, Lovney Kanguru, Diane L Ritchie, Anna M Molesworth   +4 more
doaj   +1 more source

The human spongiform encephalopathies [PDF]

Romanian Journal of Neurology, 2018
The human spongiform encephalopathies are a group of heterogenous, usually fatal diseases, characterized by a unique pathogenetic mechanism and distinct clinical presentation. They are classified into sporadic, familial and acquired forms.
Mavroudis Ioannis, Petrides Foivos, Kazis Dimitrios   +2 more
doaj   +1 more source

Characterization of Sporadic Creutzfeldt-Jakob Disease and History of Neurosurgery to Identify Potential Iatrogenic Cases

Emerging Infectious Diseases, 2020
We previously reported a phenotype of Creutzfeldt-Jakob disease (CJD), CJD-MMiK, that could help identify iatrogenic CJD. To find cases mimicking CJD-MMiK, we investigated clinical features and pathology of 1,155 patients with diagnosed sporadic CJD or ...
Tsuyoshi Hamaguchi, Kenji Sakai, Atsushi Kobayashi, Tetsuyuki Kitamoto, Ryusuke Ae, Yosikazu Nakamura, Nobuo Sanjo, Kimihito Arai, Mizuho Koide, Fumiaki Katada, Masafumi Harada, Hiroyuki Murai, Shigeo Murayama, Tadashi Tsukamoto, Hidehiro Mizusawa, Masahito Yamada   +15 more
doaj   +1 more source

EEG observations in probable sporadic CJD

Annals of Indian Academy of Neurology, 2020
Introduction: Sporadic Creutzfeldt Jakob Disease, the most common reported prion disease, is a fatal neurodegenerative disease caused by the misfolding of protein PrPC to PrPSC.
Ravindranadh Chowdary Mundlamurri, Rutul Shah, M Sharath Adiga, Aparijita Chatterjee, Bhargava Gautham, K Raghavendra, A Ajay, Anita Mahadevan, Karthik Kulanthaivelu, Sanjib Sinha   +9 more
doaj   +1 more source

Barriers to Creutzfeldt-Jakob Disease Autopsies, California

Emerging Infectious Diseases, 2004
Creutzfeldt-Jakob disease (CJD) surveillance relies on autopsy and neuropathologic evaluation. The 1990–2000 CJD autopsy rate in California was 21%. Most neurologists were comfortable diagnosing CJD (83%), but few pathologists felt comfortable diagnosing
Janice K. Louie, Shilpa S. Gavali, Ermias D. Belay, Rosalie Trevejo, Lucinda H. Hammond, Lawrence B. Schonberger, Duc J. Vugia   +6 more
doaj   +1 more source